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Cyclic Enkephalins with a Diversely Substituted Guanidine Bridge or a Thiourea Bridge: Synthesis, Biological and Structural Evaluations

Youness Touati-Jallabe , Engin Bojnik , Baptiste Legrand , Elodie Mauchauffee , Nga N. Chung , et al.
Journal of Medicinal Chemistry, 2013, 56 (14), pp.5964-5973. ⟨10.1021/jm4008592⟩
Journal articles hal-01498205v1
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Analyse d'interactions moléculaires par RMN : Étude de la DHFR en présence d'osmolytes et structures de pseudopeptides antimicrobiens en environnement membranaire

Baptiste Legrand
Biochimie [q-bio.BM]. Université de Rennes I, 2009. Français. ⟨NNT : ⟩
Theses tel-00453405v1

A Straightforward Strategy to Substitute Amide Bonds by 1,2,3 Triazoles in Peptaibols Analogs Using Aibψ[Tz]-Xaa Dipeptides

Khoubaib Ben Haj Salah , Baptiste Legrand , Sanjit Das , Jean Martinez , Nicolas Inguimbert
Biopolymers, 2015, http://onlinelibrary.wiley.com/doi/10.1002/bip.22641/abstract. ⟨10.1002/bip.22641⟩
Journal articles istex hal-01140841v1

Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives

Cécile Echalier , Alexandra Kalistratova , Jeremie Ciccione , Aurelien Lebrun , Baptiste Legrand , et al.
RSC Advances, 2016, ⟨10.1039/c6ra06075g⟩
Journal articles hal-01345976v1

Pseudohexapeptides cycliques antimicrobiens : interactions lipidiques.

Liza Mouret , Baptiste Legrand , Mathieu Laurencin , M. Baudy-Floc'H , Arnaud Bondon
GEIMM 13, May 2008, MITTELWIHR, France
Conference papers hal-00361274v1

Etude par RMN de l'impact des osmoprotecteurs sur la cinétique catalytique et la dynamique de la protéine DHFR.

Baptiste Legrand , Stéphanie Renaud , Christophe Tascon , Sylvie Bonnassie , Carlos Blanco , et al.
3èmes Rencontres Biologie-Physique du Grand Ouest, Jun 2007, Batz / Mer, France
Conference papers hal-00457061v1

Pseudo-hexapeptides cycliques antimicrobiens : interactions lipidiques. Groupe d'études des Interactions Molécules.

Baptiste Legrand , Liza Mouret , M. Laurencin , M. Baudy Floc'H , Arnaud Bondon
Groupe d'études des Interactions Molécules – Membranes, GEIMM XIII, May 2008, Mittelwihr, France
Conference papers hal-00457762v1

Silaproline Helical Mimetics Selectively Form an All-trans PPII Helix

Charlotte Martin , Baptiste Legrand , Aurélien Lebrun , Dorothée Berthomieu , Jean Martinez , et al.
Chemistry - A European Journal, 2014, 20 (44), pp.1420-14244. ⟨10.1002/chem.201404820⟩
Journal articles istex hal-01078148v1
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Towards the total synthesis of trichormamide A, a cyclic undecapeptide

Michel Gaillard , Sanjit Das , Mahamadou Djibo , Delphine Raviglione , Christian Roumestand , et al.
Tetrahedron Letters, 2018, 59 (41), pp.3713 - 3718. ⟨10.1016/j.tetlet.2018.09.010⟩
Journal articles hal-01906499v1

FT-​IR and NMR structural markers for thiazole-​based γ-​peptide foldamers

Clément Bonnel , Baptiste Legrand , Jean-Louis Bantignies , Hugo Petitjean , Jean Martinez , et al.
Organic & Biomolecular Chemistry, 2016, 14 (37), pp.8664. ⟨10.1039/C6OB01594H⟩
Journal articles hal-01398165v1

Prospect of Thiazole‐based γ‐Peptide Foldamers in Enamine Catalysis: Exploration of the Nitro‐Michael Addition

Julie Aguesseau‐kondrotas , Matthieu Simon , Baptiste Legrand , Jean‐louis Bantigniès , Young Kee Kang , et al.
Chemistry - A European Journal, 2019, 25 (30), pp.7396-7401. ⟨10.1002/chem.201901221⟩
Journal articles hal-02167326v1

Auto-assemblages pseudopeptidiques à activité antimicrobienne.

M. Laurencin , Baptiste Legrand , Arnaud Bondon , C. Zatylny-Gaudin , Y. Arlot-Bonnemains , et al.
1ères Journées aux interfaces Chimie- Biologie - Biophysique (ChimBIOPhys), Rennes, 11 et 12 décembre 2007, Dec 2007, Rennes, France
Conference papers hal-00207933v1

Insight into the antimicrobial mechanism of a de novo auto-assembling peptide.

Baptiste Legrand , M. Laurencin , E. Duval , C. Zatylny , J. Henry , et al.
7th European Biophysics Congress, Jul 2009, Genoa, Italy
Conference papers hal-00457174v1

Tailoring the Physicochemical Properties of Antimicrobial Peptides onto a Thiazole-Based γ-Peptide Foldamer

Clément Bonnel , Baptiste Legrand , Matthieu Simon , Margaux Clavié , Agnès Masnou , et al.
Journal of Medicinal Chemistry, 2020, 63 (17), pp.9168-9180. ⟨10.1021/acs.jmedchem.0c00077⟩
Journal articles hal-02946093v1
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A bicyclic unit reversal to stabilize the 12/14-helix in mixed homochiral oligoureas

Pierre Milbeo , Matthieu Simon , Claude Didierjean , Emmanuel Wenger , Emmanuel Aubert , et al.
Chemical Communications, 2020, 56 (57), pp.7921-7924. ⟨10.1039/d0cc02902e⟩
Journal articles hal-03080580v1

Etude du mécanisme d'action d'un peptide antimicrobien de novo

Baptiste Legrand , M. Laurencin , E. Duval , Joe Sarkis , V. Vié , et al.
Réunion jointes des groupes thématique "Magnétisme Nucléaire et Biologie" et "Biologie Structurale des Protéines, Jun 2009, Dourdan, France
Conference papers hal-00457800v1

Mixed oligoureas based on constrained bicyclic and acyclic β-amino acids derivatives: on the significance of the subunit configuration for folding.

Christophe André , Baptiste Legrand , Laure Moulat , Emmanuel Wenger , Claude Didierjean , et al.
Chemistry - A European Journal, 2013, 19 (50), pp.16963-71. ⟨10.1002/chem.201302829⟩
Journal articles istex hal-00968796v1
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1-Aminobicyclo[2.2.2]octane-2-carboxylic acid and derivatives as chiral constrained bridged scaffolds for foldamers and chiral catalysts

Pierre Milbeo , Jean Martinez , Muriel Amblard , Monique Calmès , Baptiste Legrand
Accounts of Chemical Research, 2021, 54 (3), pp.685-696. ⟨10.1021/acs.accounts.0c00680⟩
Journal articles hal-03371473v1
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Quantifying ecosystem capacity, modulation by agricultural practices and actual use of ecosystem services by farmers

Manon Dardonville , Christian Bockstaller , Baptiste Legrand , Olivier Therond
EASY Conference, Groupe « Ecologie & Agriculture » de la Société Française d’Ecologie (Sfe), Ecology & Agriculture Summit for Young scientists, 2019, Nice, France
Conference papers hal-02947656v1

Turning Peptide Sequences into Ribbon Foldamers by a Straightforward Multicyclization Reaction

Vincent Martin , Baptiste Legrand , Lubomir Vezenkov , Mathéo Berthet , Gilles Subra , et al.
Angewandte Chemie International Edition, 2015, 54 (47), pp.13966-13970. ⟨10.1002/anie.201506955⟩
Journal articles istex hal-01946536v1

Antimicrobial cyclic pseudopeptides including aza-β3-amino acids

Mathieu Laurencin , Baptiste Legrand , Liza Mouret , Y. Fleury , Arnaud Bondon , et al.
ICAR 2010, Nov 2010, Valladolid, Spain. pp.365-366
Conference papers hal-00873041v1

Enhancing the Antimicrobial Activity of Alamethicin F50/5 by Incorporating N-terminal Hydrophobic Triazole Substituents.

Sanjit Das , Khoubaib Ben haj salah , Emmanuel Wenger , Jean Martinez , Jules Kotarba , et al.
Chemistry - A European Journal, 2017, 23 (71), pp.17964-17972. ⟨10.1002/chem.201703569⟩
Journal articles hal-03596125v1

Incorporation of aza-beta3-amino acid into 26RFa(20-26), the endogenous ligand of GPR103: structural analysis. Peptides 2008, Proceedings of the 30th European Peptide Symposium. pp 242-243

Olivier Tasseau , Baptiste Legrand , Arnaud Bondon , Jérôme Leprince , Hubert Vaudry , et al.
2009
Books hal-01974231v1
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The HslV Protease from Leishmania major and Its Activation by C-terminal HslU Peptides

Ndeye Kebe , Krishnananda Samanta , Priyanka Singh , Josephine Lai-Kee-Him , Viviana Apicella , et al.
International Journal of Molecular Sciences, 2019, 20 (5), pp.1021. ⟨10.3390/ijms20051021⟩
Journal articles hal-02339525v1

Etude par RMN de la cinétique catalytique et de la dynamique de la DHFR en présence d'osmoprotecteurs.

Baptiste Legrand , Stéphanie Renaud , Christophe Tascon , Sylvie Bonnassie , Carlos Blanco , et al.
Congrès de la Société Française de Biochimie et Biologie Moléculaire du groupe thématique .Magnétisme Nucléaire et Biologie, Jun 2007, Dourdan, France
Conference papers hal-00457753v1

Auto-assembling antimicrobial cyclic pseudopeptides including aza-β3-amino acids RBPGO4.

M. Laurencin , Baptiste Legrand , Liza Mouret , C. Zatylny-Gaudin , J. Henry , et al.
4 èmes Rencontres de Biologie-Physique du Grand Ouest, Jun 2009, Ile de Berder, France
Conference papers hal-00457152v1

Effect of osmolytes on the DHFR activity, structure and dynamics.

Baptiste Legrand , Stéphanie Renaud , Murielle Collen , Christophe Tascon , Sylvie Bonnassie , et al.
7th European Biophysics Congress, Jul 2009, Genoa, Italy
Conference papers hal-00457646v1

Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation

Baptiste Legrand , Loic Mathieu , Aurélien Lebrun , Soahary Andriamanarivo , Vincent Lisowski , et al.
Chemistry - A European Journal, 2014, 20 (22), pp.6713-6720. ⟨10.1002/chem.201402190⟩
Journal articles istex hal-02912610v1
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Sol-gel synthesis of collagen-inspired peptide hydrogel

Cécile Echalier , Said Jebors , Guillaume Laconde , Luc Brunel , Pascal Verdié , et al.
Materials Today, 2017, 20 (2), pp.59-66. ⟨10.1016/j.mattod.2017.02.001⟩
Journal articles hal-01516237v1

Molecular Basis of the Tfs1/Ira2 Interaction: A Combined Protein Engineering and Molecular Modelling Study

Aurélie Gombault , Fabienne Godin , Denise Sy , Baptiste Legrand , Hélène Chautard , et al.
Journal of Molecular Biology, 2007, 374 (3), pp.604-617. ⟨10.1016/j.jmb.2007.09.057⟩
Journal articles istex hal-00181161v1