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Expression and purification of FtsW and RodA from Streptococcus pneumoniae, two membrane proteins involved in cell division and cell growth, respectively

Marjolaine Noirclerc-Savoye , Cécile Morlot , Philippe Gerard , Thierry Vernet , André Zapun et al.
Protein Expression and Purification, 2003, 30 (1), pp.18-25. ⟨10.1016/S1046-5928(03)000⟩
Journal articles hal-01601007v1

In vitro reconstitution of peptidoglycan assembly from the Gram-positive pathogen Streptococcus pneumoniae.

André Zapun , Jules Philippe , Katherine A Abrahams , Luca Signor , David I Roper et al.
ACS Chemical Biology, 2013, 8 (12), pp.2688-96
Journal articles hal-01322359v1

Inhibition of Streptococcus pneumoniae penicillin-binding protein 2x and Actinomadura R39 DD-peptidase activities by ceftaroline.

Astrid Zervosen , André Zapun , Jean-Marie Frère
Antimicrobial Agents and Chemotherapy, 2013, 57 (1), pp.661-3
Journal articles hal-01322362v1
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Resistance to β-Lactams in Neisseria ssp Due to Chromosomally Encoded Penicillin-Binding Proteins

André Zapun , Cécile Morlot , Muhamed-Kheir Taha
Antibiotics, 2016, 5 (4), ⟨10.3390/antibiotics5040035⟩
Journal articles hal-01426909v1

Mechanism of β-lactam action in Streptococcus pneumoniae: the piperacillin paradox

Jules Philippe , Benoit Gallet , Cécile Morlot , Dalia Denapaite , Regine Hakenbeck et al.
Antimicrobial Agents and Chemotherapy, 2015, 59, pp.609-621. ⟨10.1128/AAC.04283-14⟩
Journal articles hal-01093880v1

In vitro reconstitution of a trimeric complex of DivIB, DivIC and FtsL, and their transient co-localization at the division site in Streptococcus pneumoniae.

Marjolaine Noirclerc-Savoye , Audrey Le Gouellec , Cécile Morlot , Otto Dideberg , Thierry Vernet et al.
Molecular Microbiology, 2004, pp.413-24
Journal articles hal-01464086v1

Substitutions in PBP2b from β-Lactam-resistant Streptococcus pneumoniae Have Different Effects on Enzymatic Activity and Drug Reactivity.

Philippe Calvez , Eefjan Breukink , David I Roper , Mélanie Dib , Carlos Contreras-Martel et al.
Journal of Biological Chemistry, 2017, 292 (7), pp.2854-2865. ⟨10.1074/jbc.M116.764696⟩
Journal articles hal-01497668v1
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Lipid Phases and Cell Geometry During the Cell Cycle of Streptococcus pneumoniae

Philippe Calvez , Juliette Jouhet , Véronique Vie , Claire Durmort , André Zapun et al.
Frontiers in Microbiology, 2019, 10, pp.351. ⟨10.3389/fmicb.2019.00351⟩
Journal articles hal-02086215v1

Central domain of DivIB caps the C-terminal regions of the FtsL/DivIC coiled-coil rod.

Soizic Masson , Thomas Kern , Audrey Le Gouellec , Cécile Giustini , Jean-Pierre Simorre et al.
Journal of Biological Chemistry, 2009, pp.27687-700
Journal articles hal-01464089v1

Reconstitution of membrane protein complexes involved in pneumococcal septal cell wall assembly.

Marjolaine Noirclerc-Savoye , Violaine Lantez , Luca Signor , Jules Philippe , Thierry Vernet et al.
PLoS ONE, 2013, 8 (9), pp.e75522
Journal articles hal-01322355v1

Penicillin-binding proteins and beta-lactam resistance

André Zapun , Pauline Macheboeuf , Thierry Vernet
Mayers D., Sobel J., Ouelette M., Lerner S. Antimicrobial Drug Resistance : Principles for the Clinic and Bench, 1 (13), Humana Press, p. 145-170, 2014
Book sections hal-01158934v1

One-Pot Two-Step Metabolic Labeling of Teichoic Acids and Direct Labeling of Peptidoglycan Reveals Tight Coordination of Both Polymers Inserted into Pneumococcus Cell Wall

Julie Bonnet , Yung-Sing Wong , Thierry Vernet , Anne-Marie Di Guilmi , André Zapun et al.
ACS Chemical Biology, 2018, 13 (8), pp.2010-2015. ⟨10.1021/acschembio.8b00559⟩
Journal articles hal-01861375v1

Automated high-throughput process for site-directed mutagenesis, production, purification, and kinetic characterization of enzymes.

Raphaël Carapito , Benoit Gallet , André Zapun , Thierry Vernet
Analytical Biochemistry, 2006, 355 (1), pp.110-6. ⟨10.1016/j.ab.2006.04.047⟩
Journal articles istex hal-00194103v1

Membrane topology of the Streptococcus pneumoniae FtsW division protein

Philippe Gerard , Thierry Vernet , André Zapun
Journal of Bacteriology, 2002, 184 (7), pp.1925-1931
Journal articles hal-01601049v1

The elongation of ovococci

Jules Philippe , Thierry Vernet , André Zapun
Microbial Drug Resistance, 2014, 20 (3), pp.215-221. ⟨10.1089/mdr.2014.0032⟩
Journal articles hal-01093390v1
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Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae

Cécile Morlot , Daniel Straume , Katharina Peters , Olav A Hegnar , Nolwenn Simon et al.
Nature Communications, 2018, 9, pp.3180. ⟨10.1038/s41467-018-05602-w⟩
Journal articles hal-01861372v1
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Common alterations in PBP1a from resistant streptococcus pneumoniae decrease its reactivity towards beta -lactams: Structural insights.

Viviana Job , Raphaël Carapito , Thierry Vernet , Andréa Dessen , André Zapun et al.
Journal of Biological Chemistry, 2007, epub ahead of print. ⟨10.1074/jbc.M706181200⟩
Journal articles hal-00195479v1

Pneumococcal beta-lactam resistance due to a conformational change in penicillin-binding protein 2x.

Raphaël Carapito , Laurent Chesnel , Thierry Vernet , André Zapun
Journal of Biological Chemistry, 2006, 281 (3), pp.1771-7. ⟨10.1074/jbc.M511506200⟩
Journal articles hal-00194094v1

Roles of pneumococcal DivIB in cell division.

Audrey Le Gouellec , Laure Roux , Daniela Fadda , Orietta Massidda , Thierry Vernet et al.
Journal of Bacteriology, 2008, pp.4501-11
Journal articles hal-01464088v1

Identical penicillin-binding domains in penicillin-binding proteins of Streptococcus pneumoniae clinical isolates with different levels of beta-lactam resistance.

Laurent Chesnel , Raphaël Carapito , Jacques Croizé , Otto Dideberg , Thierry Vernet et al.
Antimicrobial Agents and Chemotherapy, 2005, 49 (7), pp.2895-902. ⟨10.1128/AAC.49.7.2895-2902.2005⟩
Journal articles hal-00194104v1