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Multifaceted Study on a Cytochalasin Scaffold: Lessons on Reactivity, Multidentate Catalysis, and Anticancer Properties

Mehdi Zaghouani , Oscar Gayraud , Vincent Jactel , Sébastien Prevost , Ambre Dezaire , et al.
Chemistry - A European Journal, 2018, 24 (62), pp.16686-16691. ⟨10.1002/chem.201804023⟩
Journal articles hal-02135339v1
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Arpin Regulates Migration Persistence by Interacting with Both Tankyrases and the Arp2/3 Complex

Gleb Simanov , Irene Dang , Artem I Fokin , Ksenia Oguievetskaia , Valérie Campanacci , et al.
International Journal of Molecular Sciences, 2021, 22 (8), ⟨10.3390/ijms22084115⟩
Journal articles hal-03278143v1
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The trimeric coiled‐coil HSBP 1 protein promotes WASH complex assembly at centrosomes

Sai Visweshwaran , Peter Thomason , Raphaël Guérois , Sophie Vacher , Evgeny V Denisov , et al.
EMBO Journal, 2018, 37 (13), pp.e97706. ⟨10.15252/embj.201797706⟩
Journal articles hal-02266358v1

A role for Ral GTPase-activating protein subunit β in mitotic regulation

Nicolas Personnic , Goran Lakisic , Edith Gouin , Alix Rousseau , Alexis Gautreau , et al.
FEBS Journal, 2014, 281 (13), pp.2977-2989. ⟨10.1111/febs.12836⟩
Journal articles hal-01204370v1
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Gradients of Rac1 Nanoclusters Support Spatial Patterns of Rac1 Signaling

Amanda Remorino , Simon de Beco , Fanny Cayrac , Fahima Di Federico , Gaetan Cornilleau , et al.
Cell Reports, 2017, 21 (7), pp.1922-1935. ⟨10.1016/j.celrep.2017.10.069⟩
Journal articles hal-01637091v1
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Actin nucleation at the centrosome controls lymphocyte polarity.

Dorian Obino , Francesca Farina , Odile Malbec , Pablo J Sáez , Mathieu Maurin , et al.
Nature Communications, 2015, 7, pp.10969. ⟨10.1038/ncomms10969⟩
Journal articles hal-01331141v1
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CYFIP2 containing WAVE complexes inhibit cell migration

Anna Polesskaya , Arthur Boutillon , Yanan Wang , Marc Lavielle , Sophie Vacher , et al.
Preprints, Working Papers, ... hal-03014297v1
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The Arp2/3 Inhibitory Protein Arpin Is Required for Intestinal Epithelial Barrier Integrity

Sandra Chánez-Paredes , Armando Montoya-García , Karla F Castro-Ochoa , Julio García-Cordero , Leticia Cedillo-Barrón , et al.
Frontiers in Cell and Developmental Biology, 2021, 9, pp.625719. ⟨10.3389/fcell.2021.625719⟩
Journal articles hal-03278147v1
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Purification of tubulin with controlled post-translational modifications by polymerization–depolymerization cycles

Judith Souphron , Satish Bodakuntla , A. S Jijumon , Goran Lakisic , Alexis Gautreau , et al.
Nature Protocols, 2019, 14 (5), pp.1634-1660. ⟨10.1038/s41596-019-0153-7⟩
Journal articles hal-02266354v1

Direct interaction between exocyst and Wave complexes promotes cell protrusions and motility.

Marco Biondini , Amel Sadou-Dubourgnoux , Perrine Paul-Gilloteaux , Giulia Zago , Melis D Arslanhan , et al.
Journal of Cell Science, 2016, 129 (20), pp.3756-3769. ⟨10.1242/jcs.187336⟩
Journal articles hal-01452011v1

PPP2R1A Regulates Migration Persistence through the WAVE Shell Complex

Yanan Wang , Giovanni Chiappetta , Raphaël Guérois , Stéphane Romero , Matthias Krause , et al.
Preprints, Working Papers, ... hal-03823497v1
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Structural Basis of Arp2/3 Complex Inhibition by GMF, Coronin, and Arpin

Olga Sokolova , Angelina Chemeris , Siyang Guo , Salvatore L Alioto , Meghal Gandhi , et al.
Journal of Molecular Biology, 2017, 429 (2), pp.237-248. ⟨10.1016/j.jmb.2016.11.030⟩
Journal articles hal-01964479v1

Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia

Pedro Monteiro , Carine Rossé , Antonio Castro-Castro , Marie Irondelle , Emilie Lagoutte , et al.
Journal of Cell Biology, 2013, 203 (6), pp.1063 - 1079. ⟨10.1083/jcb.201306162⟩
Journal articles hal-01712237v1

Directional Collective Migration in Wound Healing Assays

Nicolas Molinie , Alexis Gautreau
Humana Press. Methods in Molecular Biology, 1749, Springer Science+Business Media, pp.11-19, 2018, Cell Migration, 978-1-4939-7700-0. ⟨10.1007/978-1-4939-7701-7_2⟩
Book sections hal-01974114v1
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Analysis of Random Migration of Cancer Cells in 3D

Sai P Visweshwaran , Alexis Gautreau
Bio-protocol , 2020
Journal articles hal-03407787v1

Molecular mechanism of Arp2/3 complex inhibition by Arpin

Fred Fregoso , Trevor van Eeuwen , Gleb Simanov , Grzegorz Rebowski , Malgorzata Boczkowska , et al.
Nature Communications, 2022, 13 (1), pp.628. ⟨10.1038/s41467-022-28112-2⟩
Journal articles hal-03804980v1
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Actin polymerization downstream of integrins: signaling pathways and mechanotransduction

Stéphane Romero , Christophe Le Clainche , Alexis Gautreau
Biochemical Journal, 2020, 477 (1), pp.1--21. ⟨10.1042/BCJ20170719⟩
Journal articles hal-02445471v1
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Assembly and Activity of the WASH Molecular Machine: Distinctive Features at the Crossroads of the Actin and Microtubule Cytoskeletons

Artem I Fokin , Alexis Gautreau
Frontiers in Cell and Developmental Biology, 2021, 9, pp.658865. ⟨10.3389/fcell.2021.658865⟩
Journal articles hal-03278130v1

Membrane protrusion powers clathrin-independent endocytosis of interleukin-2 receptor.

Cyril Basquin , Michaël Trichet , Helena Vihinen , Valérie Malardé , Thibault Lagache , et al.
EMBO Journal, 2015, 34 (16), pp.2147-61. ⟨10.15252/embj.201490788⟩
Journal articles hal-01202886v1
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A highly specific gold nanoprobe for live-cell single-molecule imaging

Cecile Leduc , Satyabrata Si , Jérémie Gautier , Martinho Soto-Ribeiro , B. Wehrle-Haller , et al.
Nano Letters, 2013, ⟨10.1021/nl304561g⟩
Journal articles hal-00796925v1
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Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling

Ilektra Kouranti , Waed Abdel Khalek , Stephani Mazurkiewicz , Irmine Loisel-Ferreira , Alexis Gautreau , et al.
International Journal of Molecular Sciences, 2022, 23 (9), pp.5151. ⟨10.3390/ijms23095151⟩
Journal articles inserm-03671394v1

The Arp2/3 inhibitory protein arpin induces cell turning by pausing cell migration

Roman Gorelik , Alexis Gautreau
Cytoskeleton, 2015, 72 (7), pp.362-371. ⟨10.1002/cm.21233⟩
Journal articles istex hal-01222824v1
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Inhibitory signalling to the Arp2/3 complex steers cell migration

Irene Dang , Roman Gorelik , Carla Sousa-Blin , Emmanuel Derivery , Christophe Guérin , et al.
Nature, 2013, 503 (7475), pp.281-4. ⟨10.1038/nature12611⟩
Journal articles hal-00920076v1
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Phosphorylation of Merlin by Aurora A kinase appears necessary for mitotic progression

Vinay Mandati , Laurence Del Maestro , Florent Dingli , Berangère Lombard , Damarys Loew , et al.
Journal of Biological Chemistry, In press, pp.jbc.RA118.006937. ⟨10.1074/jbc.RA118.006937⟩
Journal articles hal-02266353v1
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Endosomal recruitment of the WASH complex: Active sequences and mutations impairing interaction with the retromer

Emmanuèle Helfer , Michael E Harbour , Véronique Henriot , Goran Lakisic , Carla Sousa-Blin , et al.
Biology of the Cell, 2013, 105 (5), pp.191-207. ⟨10.1111/boc.201200038⟩
Journal articles istex hal-01960923v1
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Mutational drivers of cancer cell migration and invasion

Nikita M Novikov , Sofia y Zolotaryova , Alexis Gautreau , Evgeny V Denisov
British Journal of Cancer, 2020, 124, pp.102-114. ⟨10.1038/s41416-020-01149-0⟩
Journal articles hal-03278149v1

The Arp2/3 inhibitory protein Arpin is dispensable for chemotaxis

Irene Dang , Joern Linkner , Jun Yan , Daniel Irimia , Jan Faix , et al.
Biology of the Cell, 2017, 109 (4), pp.162-166. ⟨10.1111/boc.201600064⟩
Journal articles hal-01955789v1

Quantitative analysis of endosome tubulation and microdomain organization mediated by the WASH complex

Emmanuel Derivery , Alexis Gautreau
Sorting and Recycling Endosomes, 130, ELSEVIER ACADEMIC PRESS, pp.215-234, 2015, Methods in Cell Biology, 978-0-12-802829-2. ⟨10.1016/bs.mcb.2015.03.025⟩
Book sections hal-01236956v1

Nucleation, stabilization, and disassembly of branched actin networks

Alexis Gautreau , Fred Fregoso , Gleb Simanov , Roberto Dominguez
Trends in Cell Biology, 2022, 32 (5), pp.421-432. ⟨10.1016/j.tcb.2021.10.006⟩
Journal articles hal-03804978v1

HSPC300 and its role in neuronal connectivity.

Abrar Qurashi , Bahar Sahin , Pilar Carrera , Alexis Gautreau , Annette Schenck , et al.
Neural Development, 2007, 2 (1), pp.18. ⟨10.1186/1749-8104-2-18⟩
Journal articles hal-00188881v1