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Blood contains circulating cell free respiratory competent mitochondria

Zahra Al Amir Dache , Amaëlle Otandault , Rita Tanos , Brice Pastor , Romain Meddeb et al.
FASEB Journal, 2020, 34 (3), pp.3616-3630. ⟨10.1096/fj.201901917RR⟩
Journal articles hal-02504546v1

Clinical utility of circulating DNA analysis for rapid detection of actionable mutations to select metastatic colorectal patients for anti-EGFR treatment

A.R. Thierry , S. El Messaoudi , C. Mollevi , J. L. Raoul , R. Guimbaud et al.
Annals of Oncology, 2017, 28 (9), pp.2149 - 2159. ⟨10.1093/annonc/mdx330⟩
Journal articles hal-01682168v1

New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysis

Cynthia Sanchez , Matthew Snyder , Rita Tanos , Jay Shendure , Alain R Thierry et al.
npj Genomic Medicine, 2018, 3, pp.31. ⟨10.1038/s41525-018-0069-0⟩
Journal articles hal-02292243v1
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Quantifying circulating cell-free DNA in humans

Romain Meddeb , Zahra Al Amir Dache , Simon Thezenas , Amaëlle Otandault , Rita Tanos et al.
Scientific Reports, 2019, 9 (1), pp.5220. ⟨10.1038/s41598-019-41593-4⟩
Journal articles hal-02327317v1

Lipoplex and peptide-based strategies for the delivery of steric-block oligonucleotides.

Sarah Resina , Saïd Abes , John J Turner , Paul Prevot , Adrian Travo et al.
International Journal of Pharmaceutics, 2007, epub ahead of print. ⟨10.1016/j.ijpharm.2007.04.039⟩
Journal articles istex hal-00167451v1
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Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA

Ekaterina Pisareva , Lucia Mihalovičová , Brice Pastor , Andrei Kudriavtsev , Alexia Mirandola et al.
Genome Medicine, 2022, 14 (1), pp.135. ⟨10.1186/s13073-022-01125-8⟩
Journal articles hal-03877035v1
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Multi-marker analysis of circulating cell-free DNA toward personalized medicine for colorectal cancer.

Florent Mouliere , Safia El Messaoudi , Dalong Pang , Anatoly Dritschilo , Alain R Thierry et al.
Molecular Oncology, 2014, 8 (5), pp.927-41. ⟨10.1016/j.molonc.2014.02.005⟩
Journal articles inserm-01076572v1

A Step Closer to Cancer Screening by Blood Test

Alain R Thierry
Clinical Chemistry, 2018, 64 (10), pp.1420-1422. ⟨10.1373/clinchem.2018.287847⟩
Journal articles hal-02292769v1

Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

Alain Thierry , Florent Mouliere , Safia El Messaoudi , Caroline Mollevi , Evelyne El Lopez-Crapez et al.
Nature Medicine, 2014, 20 (4), pp.430-435. ⟨10.1038/nm.3511⟩
Journal articles hal-02362372v1
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Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load

Florent Mouliere , Safia El Messaoudi , Celine Gongora , Anne-Sophie Guedj , Bruno Robert et al.
Translational Oncology, 2013, 6 (3), pp.319 - 328. ⟨10.1593/tlo.12445⟩
Journal articles hal-01826199v1
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Modelling of complex biological systems in the context of genomics: an account of a multidisciplinary thematic seminar held in Montpellier (France) in April 2005

Alain Thierry , François Képès , Patrick Amar , Georgia Barlovatz-Meimon , Gilles Bernot et al.
Journal of Biological Physics and Chemistry, 2006, 6, pp.103-107
Journal articles hal-00830064v1

Recent advances in circulating nucleic acids in oncology

A. Otandault , P. Anker , Z. Al Amir Dache , V. Guillaumon , R. Meddeb et al.
Annals of Oncology, 2019, 30 (3), pp.374-384. ⟨10.1093/annonc/mdz031⟩
Journal articles hal-02462645v1

Cellular uptake and intracellular fate of antisense oligonucleotides

Alain R Thierry , E. Vives , J. P. Richard , P. Prevot , C. Martinand-Mari et al.
Current Opinion in Molecular Therapeutics, 2003, 5 (2), pp.133--138. ⟨10.1016/0962-8924(92)90100-2⟩
Journal articles istex hal-02239718v1
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Monitoring levels of circulating cell‐free DNA in patients with metastatic colorectal cancer as a potential biomarker of responses to regorafenib treatment

Brice Pastor , André Thierry , Julie Henriques , Isabelle Trouilloud , Christophe Tournigand et al.
Molecular Oncology, 2021, 15 (9), pp.2401-2411. ⟨10.1002/1878-0261.12972⟩
Journal articles hal-03216431v1
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Neutrophil Extracellular Traps and By-Products Play a Key Role in COVID-19: Pathogenesis, Risk Factors, and Therapy

Alain R Thierry , Benoit Roch
Journal of Clinical Medicine, 2020, 9 (9), pp.2942. ⟨10.3390/jcm9092942⟩
Journal articles hal-03339360v1
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Machine Learning‐Assisted Evaluation of Circulating DNA Quantitative Analysis for Cancer Screening

Rita Tanos , Guillaume Tosato , Amaelle Otandault , Zahra Al Amir Dache , Laurence Pique Lasorsa et al.
Advanced Science, 2020, 7 (18), pp.2000486. ⟨10.1002/advs.202000486⟩
Journal articles hal-03337999v1
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High Fragmentation Characterizes Tumour-Derived Circulating DNA

Florent Mouliere , Bruno Robert , Erika Arnau Peyrotte , Maguy del Rio , Marc Ychou et al.
PLoS ONE, 2011, 6 (9), pp.e23418. ⟨10.1371/journal.pone.0023418⟩
Journal articles hal-02362667v1
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Circulating DNA as a Strong Multimarker Prognostic Tool for Metastatic Colorectal Cancer Patient Management Care

Safia El Messaoudi , Florent Mouliere , Stanislas Du Manoir , Caroline Bascoul-Mollevi , Brigitte Gillet et al.
Clinical Cancer Research, 2016, 22 (12), pp.3067 - 3077. ⟨10.1158/1078-0432.CCR-15-0297⟩
Journal articles hal-01826197v1
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From bioputing to bactoputing: computing with bacteria

Victor Norris , Abdallah Zemirline , Patrick Amar , Pascal Ballet , Eshel Ben Jacob et al.
Lille Spring School on Modelling Complex Biological Systems in the Context of Genomics, Apr 2008, Paris, France. pp.123-150
Conference papers hal-00340470v1

Circulating DNA Demonstrates Convergent Evolution and Common Resistance Mechanisms during Treatment of Colorectal Cancer.

Alain R Thierry , Brice Pastor , Jiang Zhi Qin , Katsiampoura D Anastasia , Christine Parseghian et al.
Clinical Cancer Research, 2017, ⟨10.1158/1078-0432.CCR-17-0232⟩
Journal articles hal-02292236v1
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Circulating nuclear DNA structural features, origins, and complete size profile revealed by fragmentomics

Cynthia Sanchez , Benoit Roch , Thibault Mazard , Philippe Jl Blache , Zahra Al Amir Dache et al.
JCI Insight, 2021, 6, ⟨10.1172/jci.insight.144561⟩
Journal articles hal-03367566v1

The Mimic Chain Reaction

Vic Norris , Alain R Thierry , Patrick Amar , Barry I Holland , Franck Molina et al.
Journal of Molecular Microbiology and Biotechnology, 2012, 22 (5), pp.335-343. ⟨10.1159/000345328⟩
Journal articles hal-00761608v1

Computing with bacterial constituents, cells and populations: from bioputing to bactoputing

Vic Norris , Abdallah Zemirline , Patrick Amar , Jean Nicolas Audinot , Pascal Ballet et al.
Theorie in den Biowissenschaften / Theory in Biosciences, 2011, 130 (3), pp.211-228. ⟨10.1007/s12064-010-0118-4⟩
Journal articles hal-00643738v1

A Targeted Q-PCR-Based Method for Point Mutation Testing by Analyzing Circulating DNA for Cancer Management Care

Alain R Thierry
Clinical Applications of PCR, 1392, pp.1-16, 2016, Methods in Molecular Biology, 978-1-4939-3358-7. ⟨10.1007/978-1-4939-3360-0_1⟩
Book sections hal-02297734v1
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A Cell Model Suitable for a High-Throughput Screening of Inhibitors of the Wnt/β-Catenin Pathway

Marina Grimaldi , Abdelhay Boulahtouf , Corinne Prévostel , Alain R Thierry , Patrick Balaguer et al.
Frontiers in Pharmacology, 2018, 9, pp.1160. ⟨10.3389/fphar.2018.01160⟩
Journal articles hal-02282710v1
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Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer

Maya Jeitany , Cédric Leroy , Priscillia Tosti , Marie Lafitte , Jordy Le Guet et al.
EMBO Molecular Medicine, 2018, 10 (4), pp.e7918. ⟨10.15252/emmm.201707918⟩
Journal articles hal-01872978v1
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Cytotoxicity assessment, inflammatory properties, and cellular uptake of Neutraplex lipid-based nanoparticles in THP-1 monocyte-derived macrophages

Eric Berger , Dalibor Breznan , Sandra Stals , Viraj Jasinghe , David Goncalves et al.
Nanobiomedicine, 2017, 4, ⟨10.1177/1849543517746259⟩
Journal articles pasteur-01688934v1

Non-invasive pre-implantation genetic diagnosis of X-linked disorders

Said Assou , Ounissa Aït-Ahmed , Safia El Messaoudi , Alain R Thierry , Samir Hamamah et al.
Medical Hypotheses, 2014, 83, pp.506--8. ⟨10.1016/j.mehy.2014.08.019⟩
Journal articles hal-02181365v1

Switching on transgene expression by correcting aberrant splicing using multi-targeting steric-blocking oligonucleotides.

Sarah Resina , Bernard Lebleu , R. Kole , A. Travo , Alain R Thierry et al.
The Journal of Gene Medicine, 2007, 9 (6), pp.498-510. ⟨10.1002/jgm.1044⟩
Journal articles istex hal-00150536v1

Toward high yield synthesis of peptide–oligonucleotide chimera through a disulfide bridge: A simplified method for oligonucleotide activation.

Florine Cavelier , Frédéric Maurel , Françoise Debart , Alain R. Thierry , Bernard Lebleu et al.
Bioorganic and Medicinal Chemistry Letters, 2005, 15, pp.5084
Journal articles hal-00117471v1