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Fragment-Based Discovery of a Regulatory Site in Thioredoxin Glutathione Reductase Acting as “Doorstop” for NADPH Entry

Ilaria Silvestri , Haining Lyu , Francesca Fata , Giovanna Boumis , Adriana Miele et al.
ACS Chemical Biology, 2018, 13 (8), pp.2190-2202. ⟨10.1021/acschembio.8b00349⟩
Journal articles hal-02109710v1

Biophysical characterization of the complex between the iron-responsive transcription factor Fep1 and DNA

Adriana Miele , Laura Cervoni , Aline Le Roy , Antimo Cutone , Giovanni Musci et al.
European Biophysics Journal, 2021, ⟨10.1007/s00249-020-01489-y⟩
Journal articles hal-03163020v1

Analysis of the effect of microgravity on protein crystal quality: the case of a myoglobin triple mutant.

Adriana E Miele , Luca Federici , Giuliano Sciara , Federica Draghi , Maurizio Brunori et al.
Acta crystallographica Section D : Structural biology [1993-..], 2003, 59 (6), pp.982-928
Journal articles hal-01595187v1

The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis.

Giuliano Sciara , Steven G Kendrew , Adriana E Miele , Neil G Marsh , Luca Federici et al.
EMBO Journal, 2003, 22 (2), pp.205-15. ⟨10.1093/emboj/cdg031⟩
Journal articles hal-01595326v1
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The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding

Cecilia Rocchi , Camille Louvat , Adriana Miele , Julien Batisse , Christophe Guillon et al.
International Journal of Molecular Sciences, 2022, 23 (22), pp.13742. ⟨10.3390/ijms232213742⟩
Journal articles hal-03434126v1

Pichia pastoris Fep1 is a [2Fe-2S] protein with a Zn finger that displays an unusual oxygen-dependent role in cluster binding

Antimo Cutone , Barry D. Howes , Adriana E. Miele , Rossella Miele , Alessandra Giorgi et al.
Scientific Reports, 2016, 6 (31872), pp.1-12. ⟨10.1038/srep31872⟩
Journal articles hal-01541882v1
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Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis.

F. Angelucci , F. Saccoccia , M. Ardini , G. Boumis , M. Brunori et al.
Journal of Molecular Biology, 2013, 425 (22), pp.4556-68. ⟨10.1016/j.jmb.2013.09.002⟩
Journal articles pasteur-01022642v1

Large expert-curated database for benchmarking document similarity detection in biomedical literature search

Peter Brown , Aik-Choon Tan , Mohamed El-Esawi , Thomas Liehr , Oliver Blanck et al.
Database - The journal of Biological Databases and Curation, 2019, 2019, ⟨10.1093/database/baz085⟩
Journal articles hal-03600728v1

Complex landscape of protein structural dynamics unveiled by nanosecond Laue crystallography.

Dominique Bourgeois , Beatrice Vallone , Friedrich Schotte , Alessandro Arcovito , Adriana E Miele et al.
Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (15), pp.8704-9. ⟨10.1073/pnas.1430900100⟩
Journal articles hal-01595186v1

Pattern of cavities in globins: the case of human hemoglobin.

Carmelinda Savino , Adriana E Miele , Federica Draghi , Kenneth A Johnson , Giuliano Sciara et al.
Biopolymers, 2009, 91 (12), pp.1097-1107. ⟨10.1002/bip.21201⟩
Journal articles istex hal-01617675v1
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Structural and functional characterization of Schistosoma mansoni Thioredoxin.

Giovanna Boumis , Francesco Angelucci , Andrea Bellelli , Maurizio Brunori , Daniela Dimastrogiovanni et al.
Protein Science, 2011, 20 (6), pp.1069-76. ⟨10.1002/pro.634⟩
Journal articles pasteur-00975317v1
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Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target.

Giovanna Boumis , Giorgio Giardina , Francesco Angelucci , Andrea Bellelli , Maurizio Brunori et al.
Biochemical and Biophysical Research Communications, 2012, 425 (4), pp.806-11. ⟨10.1016/j.bbrc.2012.07.156⟩
Journal articles pasteur-00952042v1
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Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners

Sylvain Vallet , Adriana Miele , Urszula Uciechowska-Kaczmarzyk , Adam Liwo , Bertrand Duclos et al.
Scientific Reports, 2018, 8 (1), pp.122-149. ⟨10.1038/s41598-018-30190-6⟩
Journal articles hal-02109680v1

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of C-12 hydroxylase EryK from Saccharopolyspora erythraea.

Carmelinda Savino , Giuliano Sciara , Adriana E Miele , Steven G Kendrew , Beatrice Vallone et al.
Protein and Peptide Letters, 2008, 15 (10), pp.1138-1141. ⟨10.2174/092986608786071201⟩
Journal articles hal-01617667v1
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Hemoglobin allostery: new views on old players.

Adriana Erica Miele , Andrea Bellelli , Maurizio Brunori
Journal of Molecular Biology, 2013, 425 (9), pp.1515-26. ⟨10.1016/j.jmb.2012.12.018⟩
Journal articles pasteur-01025328v1

The oligomeric assembly of the phosphodiesterase-5 is a mixture of dimers and tetramers: A putative role in the regulation of function

Silvia Cardarelli , Adriana Erica Miele , Carlotta Zamparelli , Stefano Biagioni , Fabio Naro et al.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (10), pp.2183-2190. ⟨10.1016/j.bbagen.2018.07.010⟩
Journal articles hal-02109690v1
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Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate.

Carmelinda Savino , Linda C Montemiglio , Giuliano Sciara , Adriana E Miele , Steven G Kendrew et al.
Journal of Biological Chemistry, 2009, 284 (42), pp.29170-9. ⟨10.1074/jbc.M109.003590⟩
Journal articles hal-01617673v1
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On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases.

Fulvio Saccoccia , Francesco Angelucci , Giovanna Boumis , Maurizio Brunori , Adriana E Miele et al.
Journal of Inorganic Biochemistry, 2012, 108, pp.105-11. ⟨10.1016/j.jinorgbio.2011.11.005⟩
Journal articles pasteur-00952028v1
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Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin.

Fulvio Saccoccia , Patrizio Di Micco , Giovanna Boumis , Maurizio Brunori , Ilias Koutris et al.
Structure, 2012, 20 (3), pp.429-39. ⟨10.1016/j.str.2012.01.004⟩
Journal articles pasteur-00952065v1