Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Organic & Biomolecular Chemistry Année : 2019

Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties

Résumé

An original gram-scale synthesis of O-acetylated forms of coelenterazine, furimazine or hydroxy-bearing analogues of luciferins is described. The comparison over two hours of their bioluminescence, using the nanoKAZ/NanoLuc luciferase, provides remarkable insights useful for the selection of a substrate adapted for a given application.

Domaines

Chimie organique
Fichier principal
Vignette du fichier
OBC pour Hall 2019 (1).pdf (7.38 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

pasteur-02072739 , version 1 (23-10-2019)

Identifiants

Citer

Eloi Coutant, Sophie Goyard, Vincent Hervin, Glwadys Gagnot, Racha Baatallah, et al.. Gram-scale synthesis of luciferins derived from coelenterazine and original insights into their bioluminescence properties. Organic & Biomolecular Chemistry, 2019, 15, ⟨10.1039/c9ob00459a⟩. ⟨pasteur-02072739⟩
220 Consultations
517 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More