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                <term xml:lang="en">salt iodine content</term>
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                <term xml:lang="en">iodine status</term>
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              <p>Universal salt iodization (USI) was adopted in Madagascar in 1995 within the framework of a worldwide policy to eliminate iodine deficiency disorders. Despite early USI adoption, there are no representative data on the iodine status of the Malagasy population. The aims of this study were to determine the iodine status of the Malagasy population and to assess the use of adequately iodized salt among households. We randomly sampled women of reproductive age (WRA) using a national, two-stage, stratified cross-sectional survey in 2014. Casual urine from WRA and salt samples from the household containing WRA were collected to measure urinary iodine concentration (UIC) and to assess household salt iodine content. Data from 1721 WRA in 1128 households were collected and analyzed. The national median UIC was 46 μg/L (interquartile range (IQR): 13-98 μg/L), indicating a moderate iodine deficiency. The median UIC was 53 μg/L (IQR: 9-89 μg/L) in pregnant women and 46 μg/L (IQR: 13-98 μg/L) in non-pregnant women. The national median iodine concentration of household salt was 10 mg/kg (IQR: 6.3-15.8 mg/kg) and 26.2% (95% CI: 22.1-31.0%) of households containing WRA used adequately iodized salt (≥15 mg/kg). Women living in households with adequately iodized salt had higher median UIC (72 μg/L vs. 50 μg/L). Iodine status was significantly lower among women from low socio-economic households. Madagascar's USI program needs to be revitalized. Implementing strategies to provide adequately iodized salt and enhancing iodized salt legislation to prevent severe complications resulting from iodine deficiency in the Malagasy population are essential.</p>
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              <org type="consortium">The authors wish to thank the Ministry of Public Health, the National Office of Nutrition, Administrative and Health Authorities in the study areas and participants. We also thank USAID Madagascar for their logistic support, “Cellule Géomatique, Unité épidémiologie et de Recherche Clinique, Institut Pasteur de Madagascar”, Pieter Jooste, Professor Michael Zimmermann, and Professor Christophe Rogier.</org>
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