Management of multipartite genomes: the Vibrio cholerae model. - Archive ouverte HAL Access content directly
Journal Articles Current Opinion in Microbiology Year : 2014

Management of multipartite genomes: the Vibrio cholerae model.

Abstract

A minority of bacterial species has been found to carry a genome divided among several chromosomes. Among these, all Vibrio species harbor a genome split into two chromosomes of uneven size, with distinctive replication origins whose replication firing involves common and specific factors. Most of our current knowledge on replication and segregation in multi-chromosome bacteria has come from the study of Vibrio cholerae, which is now the model organism for this field. It has been firmly established that replication of the two V. cholerae chromosomes is temporally regulated and coupled to the cell cycle, but the mediators of these processes are as yet mostly unknown. The two chromosomes are also organized along different patterns within the cell and occupy different subcellular domains. The selective advantages provided by this partitioning into two replicons are still unclear and are a key motivation for these studies.
Fichier principal
Vignette du fichier
COMICR-S-14-00091.pdf (2.17 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

pasteur-01163283 , version 1 (12-06-2015)

Licence

Copyright

Identifiers

Cite

Marie-Eve Val, Alfonso Soler-Bistué, Michael J Bland, Didier Mazel. Management of multipartite genomes: the Vibrio cholerae model.. Current Opinion in Microbiology, 2014, 22, pp.120-6. ⟨10.1016/j.mib.2014.10.003⟩. ⟨pasteur-01163283⟩
350 View
1293 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More