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Article Dans Une Revue Bioinformatics Année : 2009

SimCT: a generic tool to visualize ontology-based relationships for biological objects.

Résumé

We present a web-based service, SimCT, which allows to graphically display the relationships between biological objects (e.g. genes or proteins) based on their annotations to a biomedical ontology. The result is presented as a tree of these objects, which can be viewed and explored through a specific java applet designed to highlight relevant features. Unlike the numerous tools that search for overrepresented terms, SimCT draws a simplified representation of biological terms present in the set of objects, and can be applied to any ontology for which annotation data is available. Being web-based, it does not require prior installation, and provides an intuitive, easy-to-use service. AVAILABILITY: http://tagc.univ-mrs.fr/SimCT. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Dates et versions

halsde-00454253 , version 1 (08-02-2010)

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Carl Herrmann, Sèverine Bérard, Laurent Tichit. SimCT: a generic tool to visualize ontology-based relationships for biological objects.. Bioinformatics, 2009, 25 (23), pp.3197-8. ⟨10.1093/bioinformatics/btp553⟩. ⟨halsde-00454253⟩
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