Communication Dans Un Congrès Année : 2025

Sex-specific effects of different diets inducing MAFLD and treatment with the PPARα agonist elafibranor

Résumé

Background and aims: Metabolic associated fatty liver disease (MAFLD) is a liver disease characterized by fat accumulation and is often associated with obesity and type 2 diabetes. Recent studies suggest that sex may influence disease progression, although the underlying mechanisms remain unclear. This study aims to assess the sex-specific effects of different diets inducing MAFLD and the subsequent treatment with the PPARα agonist elafibranor, which has shown promising results in reducing disease severity and improving glucose homeostasis.

Dates et versions

hal-05508997 , version 1 (13-02-2026)

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Citer

I. Raho, R. Bertrand, J. Vicogne, A. Abderrahmani, C. Magnan, et al.. Sex-specific effects of different diets inducing MAFLD and treatment with the PPARα agonist elafibranor. 61st EASD Annual Meeting of the European Association for the Study of Diabetes, Sep 2025, Vienne, Austria. pp.id 580, ⟨10.1007/s00125-025-06497-1⟩. ⟨hal-05508997⟩
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