Article Dans Une Revue Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy [1994-...] Année : 2025

Visible and near infrared absorption and fluorescence studies of the adsorption and coverage of doxorubicin on single-walled carbon nanotubes

Résumé

Single-walled carbon nanotubes have been identified as promising materials for drug delivery due to their large specific surface area, their ability to pass through the cell membrane without damaging it and their physicochemical properties, allowing their surface to be easily functionalised. Additionally, their optical properties permit investigation in biological media in the near infrared (the “biological window”). In this paper, adsorption of doxorubicin on single-walled carbon nanotubes dispersed with carboxymethylcellulose salt is monitored by absorption and fluorescence spectroscopy in the visible and near infrared. We confirm that Raman-fluorescence coupled spectroscopy in the near infrared is a useful tool for probing the adsorption of drugs on single-walled carbon nanotubes in a sub-monolayer regime. By combining spectroscopic studies of doxorubicin in the visible range, we propose a protocol for quantifying the amount of adsorbed drug over a broad range of concentrations.

Fichier principal
Vignette du fichier
Chavignon_resub_unmarked_250911.pdf (2.06 Mo) Télécharger le fichier
SI_Chavignon_resub_unmarked_2509011def.pdf (1.6 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)
Licence
Origine Fichiers produits par l'(les) auteur(s)
Licence

Dates et versions

hal-05398481 , version 1 (04-12-2025)

Licence

Identifiants

Citer

Luc Chavignon, Christophe Blanc, Tiago Serodre, May Morris, Eric Anglaret. Visible and near infrared absorption and fluorescence studies of the adsorption and coverage of doxorubicin on single-walled carbon nanotubes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy [1994-..], 2025, 347, pp.127013. ⟨10.1016/j.saa.2025.127013⟩. ⟨hal-05398481⟩
221 Consultations
19 Téléchargements

Altmetric

Partager

  • More