Article Dans Une Revue Cell Biomaterials Année : 2025

Mechanosensitive interactions of tumoroids with an engineered environment promote cell proliferation and enhance drug response detection

Kristine Schauer

Résumé

Highlights

• Scalable microcavity arrays for high-content and label-free tumoroid live imaging

• Unique microcavity design drives tumoroid-microniche interactions • Microniche deformations uncover and quantify mechanosensitive tumoroid behavior

• Mechanical cues modulate tumoroid growth, metabolism, and drug sensitivity Authors

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Dates et versions

hal-05235620 , version 1 (02-09-2025)

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Emna Ouni, Alexis Peaucelle, Rasta Ghasemi, Francesco Facchinetti, Matthieu Opitz, et al.. Mechanosensitive interactions of tumoroids with an engineered environment promote cell proliferation and enhance drug response detection. Cell Biomaterials, 2025, ⟨10.1016/j.celbio.2025.100149⟩. ⟨hal-05235620⟩
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