Article Dans Une Revue Journal of Allergy and Clinical Immunology: In Practice Année : 2025

Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven European Birth Cohorts

Anne V Aurup
  • Fonction : Auteur
Aksel Karl Georg Jensen
  • Fonction : Auteur
Timothy Cadman
  • Fonction : Auteur
Morris A Swertz
  • Fonction : Auteur
Muriel Tafflet
  • Fonction : Auteur
Martine Vrijheid
  • Fonction : Auteur
John Wright
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Tiffany C Yang
  • Fonction : Auteur
David Taylor-Robinson
  • Fonction : Auteur
Lorenzo Richiardi
  • Fonction : Auteur
Anne-Marie Nybo Andersen
  • Fonction : Auteur

Résumé

What is already known about this topic? Children from disadvantaged socioeconomic circumstances have an increased risk of asthma. In the few studies that have assessed pathways to these inequalities, bronchiolitis, home environment, and perinatal factors have been identified as potential mediators.

What does this article add to our knowledge? We uniquely examined multiple potential mediators of inequalities across several European birth cohorts, with findings suggesting that maternal smoking, adverse birth outcomes, and breastfeeding duration have a consistent role in mediating social inequalities in asthma.

How does this study impact current management guidelines? Our study indicates that public health actions in the perinatal period to help mothers cease smoking, improve birth outcomes, and support breastfeeding could provide some benefit in helping to address inequalities in childhood asthma.

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Dates et versions

hal-05204376 , version 1 (08-08-2025)

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Angela Pinot de Moira, Anne V Aurup, Demetris Avraam, Daniela Zugna, Aksel Karl Georg Jensen, et al.. Understanding Social Inequalities in Childhood Asthma: Quantifying the Mediating Role of Modifiable Early-Life Risk Factors in Seven European Birth Cohorts. Journal of Allergy and Clinical Immunology: In Practice, 2025, 13 (6), pp.1385 - 1396. ⟨10.1016/j.jaip.2025.02.032⟩. ⟨hal-05204376⟩
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