Digital Twins in Pharmaceuticals: A Narrative Review with Industry Case Insights
Résumé
Background: The integration of digital twin technology is reshaping pharmaceutical innovation across R&D, manufacturing, and patient care. Objective: This narrative review synthesizes real-world applications and current literature to evaluate the impact of digital twins on pharmaceutical workflows. Methods: A structured search of publications from 2020–2024 was conducted, emphasizing industry case reports, peer-reviewed studies, and technology whitepapers. Results: Digital twins have enhanced process optimization, accelerated drug discovery, and improved clinical trial designs. However, challenges remain in regulatory alignment, data standardization, and implementation costs. Conclusion: Digital twins offer substantial potential for personalized medicine and operational excellence. Future research must address limitations in interoperability, reproducibility, and ethical use to ensure sustainable adoption.