Article Dans Une Revue European Journal of Cancer Année : 2025

Proof of concept and design of an externally controlled trial for patients with gastro-enteropancreatic neuroendocrine carcinomas based on the randomized phase II BEVANEC trial

Résumé

Randomized trials are very challenging to perform in rare cancers such as gastro-enteropancreatic neuroendocrine carcinomas. We hypothesized that the randomized BEVANEC trial of FOLFIRI + /- bevacizumab could have been designed with an external control arm (ECA) and led to similar results.

Dates et versions

hal-05062946 , version 1 (11-05-2025)

Identifiants

Citer

S. Ganame, Thomas Walter, Alain Durand, A. Lièvre, D. Tougeron, et al.. Proof of concept and design of an externally controlled trial for patients with gastro-enteropancreatic neuroendocrine carcinomas based on the randomized phase II BEVANEC trial. European Journal of Cancer, 2025, pp.115450. ⟨10.1016/j.ejca.2025.115450⟩. ⟨hal-05062946⟩
92 Consultations
0 Téléchargements

Altmetric

Partager

  • More