Article Dans Une Revue International Journal of Physiology Année : 2023

Effect of Smoking Cessation on Vascular Function by Measurement the Flow-Mediated Dilation: A Comparative Study

Résumé

Smoking predisposes to endothelial dysfunction; however smoking cessation would have a beneficial effect on cardiovascular risk. The objective of this study was to evaluate the effect of smoking cessation on vascular function. Methods: This is a comparative, prospective, descriptive, and multicenter study, carried out between March 2018 and April 2021 at two Health Services of the National Gendarmerie and at the Laboratory of Physiology and Functional Explorations of the Faculty of Medicine in Dakar, Senegal. The population included 45 consenting adult men, divided into 3 groups: active smokers, weaned smokers, and non-smokers. We assessed vascular function using the Flow Mediated Dilation (FMD) technique, which consisted of measuring the diameter of the humeral artery at rest and then every 30 seconds after its occlusion. Results: Non-smokers showed better humeral artery dilation at T1 (30 seconds after occlusion release) with a higher mean FMD than the other 2 groups (p = 0.0007). In addition, FMD kinetics showed that control subjects as well as weaned subjects had better arterial compliance (p < 0.05) compared to active smokers. FMD1 values were positively correlated with smoking cessation duration (p = 0.0411; R2 = 0.3374). Conclusion: Our results showed that stopping smoking improves vascular function and thus constitutes a means of preventing cardiovascular diseases, hence the need to promote smoking cessation in Africa and more particularly in Senegal.

Fichier principal
Vignette du fichier
Effect_of_Smoking_Cessation_on_Vascular_Function_b.pdf (303.26 Ko) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte
Licence

Dates et versions

hal-04986923 , version 1 (11-03-2025)

Licence

Identifiants

  • HAL Id : hal-04986923 , version 1

Citer

A Ba-Diop, K N Diong, F A Faye, I Diouf, M Diaw, et al.. Effect of Smoking Cessation on Vascular Function by Measurement the Flow-Mediated Dilation: A Comparative Study. International Journal of Physiology, 2023, 12 (1), pp.3473. ⟨hal-04986923⟩

Collections

30 Consultations
46 Téléchargements

Partager

  • More