Article Dans Une Revue PLoS ONE Année : 2017

Expansion by whole genome duplication and evolution of the sox gene family in teleost fish

Résumé

It is now recognized that several rounds of whole genome duplication (WGD) have occurred during the evolution of vertebrates, but the link between WGDs and phenotypic diversification remains unsolved. We have investigated in this study the impact of the teleost-specific WGD on the evolution of the sox gene family in teleostean fishes. The sox gene family, which encodes for transcription factors, has essential role in morphology, physiology and behavior of vertebrates and teleosts, the current largest group of vertebrates. We have first redrawn the evolution of all sox genes identified in eleven teleost genomes using a comparative genomic approach including phylogenetic and synteny analyses. We noticed, compared to tetrapods, an important expansion of the sox family: 58% (11/19) of sox genes are duplicated in teleost genomes. Furthermore, all duplicated sox genes, except sox17 paralogs, are derived from the teleost-specific WGD. Then, focusing on five sox genes, analyzing the evolution of coding and non-coding sequences, as well as the expression patterns in fish embryos and adult tissues, we demonstrated that these paralogs followed lineage-specific evolutionary trajectories in teleost genomes. This work, based on whole genome data from multiple teleostean species, supports the contribution of WGDs to the expansion of gene families, as well as to the emergence of genomic differences between lineages that might promote genetic and phenotypic diversity in teleosts

Fichier principal
Vignette du fichier
07e64e005f0124e342ee08951d611bd6.pdf (9.15 Mo) Télécharger le fichier
Origine Fichiers éditeurs autorisés sur une archive ouverte
Licence

Dates et versions

hal-04901182 , version 1 (02-06-2025)

Licence

Identifiants

Citer

Emilien Voldoire, Frédéric Brunet, Magali Naville, Jean-Nicolas Volff, Delphine Galiana. Expansion by whole genome duplication and evolution of the sox gene family in teleost fish. PLoS ONE, 2017, 12 (7), pp.e0180936. ⟨10.1371/journal.pone.0180936⟩. ⟨hal-04901182⟩
176 Consultations
54 Téléchargements

Altmetric

Partager

  • More