Article Dans Une Revue FEBS Letters Année : 2000

Increase in the adenine nucleotide translocase content of duckling subsarcolemmal mitochondria during cold acclimation

Résumé

Intermyofibrillar and subsarcolemmal mitochondria were isolated from duckling gastrocnemius muscle. The adenine nucleotide translocase (ANT) content of subsarcolemmal mitochondria was found to be half of that present in intermyofibrillar mitochondria. In addition, cold acclimation resulted in a 1.7-fold increase in subsarcolemmal mitochondrial ANT content, with intermyofibrillar mitochondrial ANT remaining constant. This change in mitochondrial ANT content correlates with the previously reported cold-induced change in the sensitivity of mitochondria to palmitate-inhibited ATP synthesis [Roussel et al. (1998) FEBS Lett. 439, 258^262]. It is suggested that the mitochondrial ANT content enhances or reduces the fatty acid uncoupling activity in tissue, depending on the energetic state of mitochondria.

Dates et versions

hal-04886601 , version 1 (17-01-2025)

Identifiants

Citer

Damien Roussel, François Chainier, Jean-Louis Rouanet, Hervé Barré. Increase in the adenine nucleotide translocase content of duckling subsarcolemmal mitochondria during cold acclimation. FEBS Letters, 2000, 477 (1-2), pp.141-144. ⟨10.1016/s0014-5793(00)01790-7⟩. ⟨hal-04886601⟩
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