CONTEXT: Implementing alternative practices to the use of pesticides involves work issues that can limit adoption of these practices, particularly on dairy farms. Depending on how practices change, work organization may completely change, additional skills and knowledge may be required, and system complexity may increase, inducing a higher mental workload. This can result in an excessive total workload for already overburdened farmers. OBJECTIVE: The present study examines whether work limits the implementation of alternative practices to reduce pesticide use on dairy farms, depending on the amount of change the practices require. Three work dimensions were considered: work organization, skills and knowledge, and physical and mental workload. METHODS: We used nine semi-structured interviews with crop and livestock experts in Brittany (France’s leading region for dairy production) to classify multiple categories of practices by their degree of difficulty and the type of work dimension involved, with a specific focus on three practices: using resistant crop varieties, mechanical weed control and extending crop rotations. RESULTS AND CONCLUSIONS: First, experts emphasized certain alternative practices over others depending on the institution to which they belonged. Second, the need to balance the feeding system and an increase in herd size, which is not compatible with all alternative practices, were barriers specific to dairy farms. Third, all three practices we focused on were skill- and knowledge-intensive, but in different ways. Using resistant crop varieties requires access to the right information, while mechanical weed control raises issues of training, investment or outsourcing. Finally, extending crop rotations, considered as a redesign of the production system, requires obtaining the resources, time and autonomy to think about new rotations. SIGNIFICANCE: This study shows that, in addition to work organization, other work dimensions are crucial for reducing pesticide use on dairy farms.