Gold nanoclusters Au 25 AcCys 18 normalize intracellular ROS without increasing cytoplasmic alarmin acHMGB1 abundance in human microglia and neurons
Abstract
The gold nanocluster Au25AcCys18 modulates human microglia and neuronal cells at the level of oxidative stress and protein–protein interactions (HMGB1 and TFEB). Complementary computational and biological methods reveal these interactions.