Quantifying the resources available to a quantum computer appears to be necessary to separate quantum from classical computation. Among them, entanglement, magic and coherence are arguably of great significance. We introduce path coherence as a measure of the coherent paths interferences arising in a quantum computation. Leveraging the sum-over-paths formalism, we obtain a classical algorithm for estimating quantum transition amplitudes, the complexity of which scales with path coherence. As path coherence relates to the hardness of classical simulation, it provides a new perspective on the role of coherence in quantum computational advantage. Beyond their fundamental significance, our results have practical applications for simulating large classes of quantum computations with classical computers.