Pallidin function in Drosophila surface glia regulates sleep and is dependent on amino acid availability
Pallidin function in Drosophila surface glia regulates sleep and is dependent on amino acid availability.
Résumé
In brief
The Pallidin gene is a central component of an endosomal protein complex. Li et al. provide evidence that Pallidin is required in Drosophila surface glia, the equivalent of the blood-brain barrier, to initiate sleep at the beginning of the night through regulating leucine transport and GABAergic tone on circadian clock neurons.
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