<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04778132</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-17T01:46:49+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Complex flow in the gastro-intestinal tract</title>
            <author role="aut">
              <persName>
                <forename type="first">Clément</forename>
                <surname>de Loubens</surname>
              </persName>
              <email type="md5">59266bed00673baf4c772defab34b8c1</email>
              <email type="domain">univ-grenoble-alpes.fr</email>
              <idno type="idhal" notation="string">clement-de-loubens</idno>
              <idno type="idhal" notation="numeric">172663</idno>
              <idno type="halauthorid" notation="string">30028-172663</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-4988-9168</idno>
              <idno type="IDREF">https://www.idref.fr/157838633</idno>
              <affiliation ref="#struct-1043300"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Clément</forename>
                <surname>de Loubens</surname>
              </persName>
              <email type="md5">59266bed00673baf4c772defab34b8c1</email>
              <email type="domain">univ-grenoble-alpes.fr</email>
            </editor>
            <funder ref="#projanr-55829"/>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2024-11-12 15:39:38</date>
              <date type="whenModified">2025-09-27 19:58:46</date>
              <date type="whenReleased">2024-11-12 15:39:38</date>
              <date type="whenProduced">2023-10-16</date>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="484214">
                <persName>
                  <forename>Clément</forename>
                  <surname>de Loubens</surname>
                </persName>
                <email type="md5">59266bed00673baf4c772defab34b8c1</email>
                <email type="domain">univ-grenoble-alpes.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04778132</idno>
            <idno type="halUri">https://hal.science/hal-04778132</idno>
            <idno type="halBibtex">deloubens:hal-04778132</idno>
            <idno type="halRefHtml">&lt;i&gt;Complex rheology in biological systems&lt;/i&gt;, Royal Society, Oct 2023, Leeds (Angleterre), United Kingdom</idno>
            <idno type="halRef">Complex rheology in biological systems, Royal Society, Oct 2023, Leeds (Angleterre), United Kingdom</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="LRP" corresp="INPG">Laboratoire Rhéologie et Procédés</idno>
            <idno type="stamp" n="UGA-EPE">Université Grenoble Alpes [2020-*]</idno>
            <idno type="stamp" n="ANR">ANR</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="invited" n="1">Yes</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
            <note type="proceedings" n="0">No</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Complex flow in the gastro-intestinal tract</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Clément</forename>
                    <surname>de Loubens</surname>
                  </persName>
                  <email type="md5">59266bed00673baf4c772defab34b8c1</email>
                  <email type="domain">univ-grenoble-alpes.fr</email>
                  <idno type="idhal" notation="string">clement-de-loubens</idno>
                  <idno type="idhal" notation="numeric">172663</idno>
                  <idno type="halauthorid" notation="string">30028-172663</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-4988-9168</idno>
                  <idno type="IDREF">https://www.idref.fr/157838633</idno>
                  <affiliation ref="#struct-1043300"/>
                </author>
              </analytic>
              <monogr>
                <meeting>
                  <title>Complex rheology in biological systems</title>
                  <date type="start">2023-10-16</date>
                  <date type="end">2023-10-17</date>
                  <settlement>Leeds (Angleterre)</settlement>
                  <country key="GB">United Kingdom</country>
                </meeting>
                <respStmt>
                  <resp>conferenceOrganizer</resp>
                  <name>Royal Society</name>
                </respStmt>
                <imprint/>
              </monogr>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="halDomain" n="phys.meca.mefl">Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph]</classCode>
              <classCode scheme="halTypology" n="COMM">Conference papers</classCode>
              <classCode scheme="halOldTypology" n="COMM">Conference papers</classCode>
              <classCode scheme="halTreeTypology" n="COMM">Conference papers</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>The gastrointestinal (GI) tract actively transports food along different organs to mix it with secretions and break down food particles, which can then be absorbed by the body while waste is eliminated. This involves a variety of biological, chemical, and physical phenomena. Understanding flow phenomena in the GI tract is important for human health, as it can impact drug delivery, the spatiotemporal organization of the microbiota, and lead to health problems related to GI motility dysfunction.This presentation demonstrates how the gastrointestinal tract handles complex flow by providing two examples: one at the organ scale and the other at the microscopic scale.The first example aims to demonstrate how complex fluid dynamics modelling of video defecography can aid in diagnosing defecation disorders. A two-dimensional patient-specific simulation was developed based on standard X-ray video defecographies to quantify velocity, pressure, and stress fields during defecation for patients with normal and pathological defecatory function. The results showed that normal defecation involved a proximal–distal pressure gradient from both the anorectal junction and the anal canal, with the flow dominated by shear-thinning viscous properties. Impaired defecations were also simulated and compared to normal defecation, leading to a discussion of critical factors that could aid in effective medical management.In the second example, the focus is on how fluid is transported and mixed at small scales using microscopic finger-like structures, the so-called villi. A numerical model was developed to simulate flow and mixing due to the active movement of villi. By using the physiological pattern of contractions, it was shown that villi can either transport fluid in the longitudinal direction of the small intestine and/or induce radial mixing. These phenomena are due to a combination of geometric effects (wave propagation) and inertia at moderate Reynolds number.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-1043300" status="VALID">
          <idno type="IdRef">184670020</idno>
          <idno type="RNSR">199511964F</idno>
          <idno type="ROR">https://ror.org/044ggyg50</idno>
          <orgName>Laboratoire Rhéologie et Procédés</orgName>
          <orgName type="acronym">LRP</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>363 rue de la Chimie BP 53 38041 GRENOBLE CEDEX 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.laboratoire-rheologie-et-procedes.fr</ref>
          </desc>
          <listRelation>
            <relation name="UMR5520" active="#struct-441569" type="direct"/>
            <relation active="#struct-1042703" type="direct"/>
            <relation active="#struct-1043329" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1042703" status="VALID">
          <idno type="IdRef">240648315</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes</orgName>
          <orgName type="acronym">UGA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Adresse CS 40700 - 38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-grenoble-alpes.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1043329" status="VALID">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1042703" type="direct"/>
          </listRelation>
        </org>
      </listOrg>
      <listOrg type="projects">
        <org type="anrProject" xml:id="projanr-55829" status="VALID">
          <idno type="anr">ANR-21-CE45-0015</idno>
          <orgName>TransportGut</orgName>
          <desc>Modélisation muli-échelle du transport dans le système digestif</desc>
          <date type="start">2021</date>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>