A povarov-type reaction to access tetrahydroquinolines from <i>N</i>-benzylhydroxylamines and alkenes in HFIP - Archive ouverte HAL
Article Dans Une Revue Chemical Communications Année : 2024

A povarov-type reaction to access tetrahydroquinolines from N-benzylhydroxylamines and alkenes in HFIP

Résumé

Here, we report the synthesis of tetrahydroquinolines between newly developed N-benzylhydroxylamine reagents and alkenes using HFIP as a solvent. This transformation is notably applicable to highly electronically deactivated styrenes and aliphatic alkenes, expanding the range of tetrahydroquinolines attainable.

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Chimie organique
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hal-04762366 , version 1 (31-10-2024)

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Valentyn Pozhydaiev, Daniella Al-Othman, Joseph Moran, David Lebœuf. A povarov-type reaction to access tetrahydroquinolines from N-benzylhydroxylamines and alkenes in HFIP. Chemical Communications, 2024, 60 (76), pp.10504 - 10507. ⟨10.1039/d4cc04014g⟩. ⟨hal-04762366⟩
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