Permafrost-affected rockwalls are increasingly impacted by the effects of climate change and rising air temperature leading to rock slope failures. These events pose a threat for human lives and infrastructure, which underlines the need of better knowledge about their triggering mechanism and propagation.  The aim of this study was to propose a mapping approach of susceptible release areas of rock slope failures and resulting runout distances at a regional scale. This information helps identifying hotspots for subsequent hazard assessment.To do so, we used an inventory of 1389 rock slope failures (volume > 102 m3)recorded in the Mont-Blanc massif from 2007 to 2019 and determined the topographical and permafrost conditions that are most prone to their triggering using a digital terrain model and a permafrost map. These conditions are used in a multi-criteria GIS approach to identify potential unstable slopes at the French Alps scale. Then, the potential release area map is used as input to map the runout of potential events, using a propagation model based on a normalised area dependant energy line principle. The resulting maps of release and propagation areas will be used to point out human assets (mountaineering routes, high mountain infrastructure, tourism areas) and lakes (that can provoke cascading hazards) which could be impacted by rock slope failure hazards.This work is a first step to identify hot spots for a regional hazard assessment where more detailed analyses will be required to evaluate potential risks at a local scale.