METHODS FOR TREATING TUMORS
Résumé
The present disclosure relates to methods of treating tumors. In particular, the present disclosure relates to a method of treating a tumor in a subject in need thereof by ionizing radiation, the method comprising: (i) injecting a first therapeutically effective amount of nanoparticles containing a high Z element as a radiosensitizer into the subject in need thereof for a period of 2-10 days prior to a first irradiation of the tumor, (ii) within 1-12 hours prior to the first irradiation of the tumor, injecting a second therapeutically effective amount of identical or different nanoparticles containing high Z element, and (iii) irradiating the tumor of the subject with a therapeutically effective amount of radiation; wherein the nanoparticles containing high element Z are nanoparticles containing an element having an atomic Z number higher than 40, and the nanoparticles have an average hydrodynamic diameter lower than 10 nm.