Poster De Conférence Année : 2024

Is pressurized intraperitoneal aerosol chemotherapy (PIPAC) feasible in a rabbit model of gastric peritoneal metastases?

Résumé

Currently, peritoneal metastases (PM) represent a poor prognosis in cancer and chemotherapy techniques are very limited (Cortés-Guiral et al 2021 Nat Rev Dis Primers). Pressurized intra-peritoneal aerosol chemotherapy (PIPAC) appears to be a new and more effective treatment method (Kepenekian et al 2022 Nat rev Clin Oncol). However, the development of a new protocol requires animal experiments (Taibi et al 2019 Plos One). In this study, the feasibility of the technique on the healthy lagomorph model was tested with a view to subsequently testing the efficacy of this procedure on a lagomorph model with peritoneal metastases. The aim was to assess the safety and viability of repetitive PIPAC procedures in a rabbit model.

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Dates et versions

hal-04717930 , version 1 (02-10-2024)

Identifiants

  • HAL Id : hal-04717930 , version 1

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Sylvia M. Bardet, Marie-Laure Perrin, Matteo Brandy, C. Yardin, Sylvaine Durand-Fontanier, et al.. Is pressurized intraperitoneal aerosol chemotherapy (PIPAC) feasible in a rabbit model of gastric peritoneal metastases?. PSOGI-ISSPP 2024, Sep 2024, Lyon, France. 2024. ⟨hal-04717930⟩
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