Expression pattern of the drm/gremlin gene during chicken embryonic development - Archive ouverte HAL
Article Dans Une Revue Mechanisms of Development Année : 2001

Expression pattern of the drm/gremlin gene during chicken embryonic development

Résumé

The drm gene encodes a cystine knot-containing secreted and cell membrane-associated glycoprotein shown to be an antagonist of BMPs. Drm was recently reported to play a crucial role in limb bud development, by its capacity to bind BMPs. Here, we have studied the expression pattern of drm transcripts during chicken development, by using whole-mount in situ hybridization. We show that, from stage 22HH to stage 26HH, in addition to limb buds, drm is expressed in cephalic neural crest-derived branchial arches I, II and III, in the medio-dorsal lip of the myotome and in the superficial dermatome

Dates et versions

hal-04717458 , version 1 (01-10-2024)

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Citer

Boris Bardot, Laure Lecoin, Emmanuelle Huillard, Georges Calothy, Maria Marx. Expression pattern of the drm/gremlin gene during chicken embryonic development. Mechanisms of Development, 2001, 101 (1-2), pp.263-265. ⟨10.1016/s0925-4773(00)00571-2⟩. ⟨hal-04717458⟩

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