Herein, we have presented a new manganese(III) metalloporphyrin, named, based on the X-ray molecular structure, the bis(4-dimethylaminopyridine)[meso-tetra(para-chlorophenyl)porphyrinato]manganese(III) triflate 1.56 chloroform solvate 0.22 n-hexane solvate 0.22 hydrate with the following formula:[MnIII(TClPP)(DMAP)2] (SO3CF3)and sdot;0.22(C6H14)and sdot;1.56(CHCl3)and sdot;0.22(H2O) (complex I). This coordination compound was characterized by FT-IR and cyclic voltammetry. The dichloromethane solution UV/Vis spectrum of I is typical of a Mn(III) high-spin (S = 2) porphyrin complex with a redshifted Soret band with lambda max value of 487 nm. The single crystal X-diffraction technique was used to determine the molecular structure of our new Mn(III) bis(DMAP) porphyrin complex. Electron paramagnetic resonance (EPR) spectroscopy confirms that this new 3d4 Mn(III) metalloporphyrin (a non-Kramers system) in solid state is high-spin (S = 2). DFT/TD-DFT calculations on complex I were investigated, including (i) the molecular structure optimization using the DFT/B3LYP-D3/LanL2DZ level of theory, (ii) the frontier molecular orbital calculations and the deduction of the global indices of activities, (iii) the molecular electronic potential analysis (MEP), and (iv) the QTAIM and NCI-RDG analyses. Furthermore, complex I was tested against diverse amino acids of the selected Bcl-2 proteins using docking calculations.