Article Dans Une Revue JNCI: Journal of the National Cancer Institute Année : 2024

Geriatric assessment and quality of life for 2 years in older patients with head and neck cancer

Didier Salvan
  • Fonction : Auteur
Laurence Chaumette
  • Fonction : Auteur
Elisabeth Sauvaget
  • Fonction : Auteur
Aurelien Minard
  • Fonction : Auteur
Amelie Anota
  • Fonction : Auteur
Lydia Brugel
  • Fonction : Auteur

Résumé

# The Author(s) 2024.Due to the location and toxicity of treatments, head and neck cancer (HNC) has a major impact on quality of life (QoL). Objective: to assess the effects of geriatric-assessment (GA)-driven interventions on QoL over 2 years in older adults with HNC. EGeSOR was a randomized study of HNC patients aged ≥65, receiving a pretreatment GA, a geriatric intervention and follow-up (intervention) or standard of care (control). The primary endpoint was QoL score using the European Organisation for Research and Treatment of Canceru2019s (EORTC QLQ-C30) and HNC (QLQ-HN35) QoL questionnaires over 24 months. In total, 475 patients were included (median age: 75.3; women: 31%; oral cancer: 44%). QoL scores improved over 24 months with various trajectories, without significant differences between the groups. A total of 74% of patients (interventional group) did not receive the complete intervention. Cancer characteristics, functional status, and risk of frailty were associated with change in the Global Health Status QoL score. There is a need to develop an alternative model of implementation such as patient-centered health-care pathways.

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Dates et versions

hal-04684907 , version 1 (03-09-2024)

Identifiants

Citer

Charlotte Lafont, Elena Paillaud, Philippe Caillet, Marie Laurent, Florence Canouï-Poitrine, et al.. Geriatric assessment and quality of life for 2 years in older patients with head and neck cancer. JNCI: Journal of the National Cancer Institute, 2024, 116 (5), pp.758-763. ⟨10.1093/jnci/djae027⟩. ⟨hal-04684907⟩
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