Fluoride-Catalyzed Cross-Coupling of Silylamides to CF3 -Acrylates: Access to Highly Functionalized Trifluoromethylated and Quaternary Fluorinated Molecular Architectures
Résumé
A direct and simple catalytic coupling of non-fluorinated and fluorinated silylbutenamides with-CF3 -unsaturated esters mediated by fluoride ion was carried out. The transformation proceeded with excellent yields to afford new highly-functionalized trifluoromethylated and quaternary fluorinated products.