Comparative analysis of statistical methods for determining Deep Brain Stimulation sweet spots
Résumé
The precise location of the optimal target, or sweet spot, for Deep Brain Stimulation (DBS) is still unknown. However, its determination plays a pivotal role in guiding algorithms for the automatic programming of DBS parameters. Several studies have approached this problem, mainly employing t-test and Wilcoxon test to obtain probabilistic stimulation maps. However, a thorough assessment of the chosen statistical method’s influence on the sweet spot extracted from group analysis is still missing. The objective of this study is to compare the outcomes of the above mentioned statistical tests applied to DBS patients data.
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