The verification/prediction by numerical simulation of the resistance of large-scale metal structures subjected to extreme loading (e.g. accidental mechanical overload) that can lead to failure constitutes a major issue in the transport, energy, and defense sectors. This work aims to develop a three-dimensional numerical methodology (i) capable of macroscopically accounting for the various dissipative mechanisms of plasticity and damage until failure, (ii) formulated within the framework of large deformation, (iii) implemented in a commercial computation code, and (iv) mesh-objective. The commercial computational code is ABAQUS-std, and the methodology is implemented as a user finite element (UEL). Geometric non-linearities are treated within the framework of an updated Lagrangian formulation (ULF). The more or less diffuse damage phase is described by the Gurson-Tvergaard-Needleman (GTN) microporous plasticity model with standard finite element (FE). The micro-void coalescence phase-induced dilation/shear band is described using an original volumetric cohesive extended finite element method approach (VCZM-XFEM). The progressive loss of cohesion leading to ultimate cracking is treated with extended finite element method (XFEM). Particular attention is paid to transition criteria (damage to localization, localization to cracking), to the orientation of the localization plane (especially in Mode II), to the cohesive zone model and to techniques for overcoming numerical difficulties (volumetric locking, numerical integration). The so-built 3D-FS-GTN-VCZM-XFEM unified methodology is capable of reproducing the degradation mechanisms, and, the failure surface shape and orientation in large elasto-plastic deformation of structures typical of laboratory tests, even for fairly coarse meshes.