Impedance analysis is a powerful technique that has become increasingly important in various applications, it represents a leap forward in the field of electronic measurments and diagnostics. In this work, we present the development of miniaturized, multiplexed, and connected platform for impedance spectroscopy. Designed for online measurements and adapted to wireless network architectures, our platform has been tested and optimized to be used for multi-selective chemical organic sensor nodes. This compact and versatile circuit is built from low cost and low power consumption (250 mW) microelectronics components that achieve long duration operability (5 days and 16 h) without compromising on sensor measurement accuracy and precision. We used the well-known impedance network analyzer AD5933 (Analog Devices, Norwood, MA, USA) chip which can measure a spectrum of impedances in the range 5 kHz to 100 kHz. The proposed system is based on ESP32-C3 Microcontroller enabling the management of the AD5933 through its I2C interface. Our system benefits from two multiplexer components CD74HC4067 allowing calibration process and the interface of 15 conductimetric sensors with real time acquisition (less than 90 ms per acquisition). The system is capable of relaying information through the network for data analysis and storage. The paper describes the microelectronics design, the impedance response over time, the measurement’s sensitivity and accuracy and the testing of the platform with embedded chemical sensors for gas classification and recognition.