This chapter reflects on the concept of Urbicide by analyzing experiences of inequality in daily mobility in metropolises throughout Latin America. It appears that despite allowing for improvements, contemporary transformations (particularly under the discourse of sustainable mobility) also have negative effects, either unwanted or not, that marginalize certain population groups. Three phenomena (or forms of Urbicide) are highlighted in this chapter: the deficiencies of large infrastructure projects in terms of costs, effectiveness, and coverage; the implications of the formalization of informal modes of transport; and finally, the forms of exclusion in the promotion of active mobility.