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Communication Dans Un Congrès Année : 2024

Using Real Time Phase contrast MRI to investigate CSF oscillations and aqueductal pressure gradients during free breathing

Résumé

Motivation CSF dynamics is complex and regulates intracranial pressure. Pressure difference dynamics between the third and fourth ventricles (ΔPt) drives CSF oscillations in the aqueduct. MRI can quantify aqueduct anatomy and CSF oscillations. Goal To quantify ΔPt during free-breathing by combining MRI anatomical imaging with real-time phase-contrast MRI. Approach We developed a dedicated software to obtain: CSF flows dynamics Q(t), morphology of the aqueduct, its flow resistance (R) and ΔPt which equal Qt·R. Cardiac and breathing contributions to ΔPt were investigated in volunteers. Results Contributions to ΔPt were 12.3 Pa and 9.5 Pa from cardiac and breathing respectively.
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Dates et versions

hal-04627954 , version 1 (28-06-2024)

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  • HAL Id : hal-04627954 , version 1

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Pan Liu, Kimi Owashi, Serge Metanbou, Cyrille Capel, Olivier Balédent. Using Real Time Phase contrast MRI to investigate CSF oscillations and aqueductal pressure gradients during free breathing. ISMRM 2024, International Society for Magnetic Resonance in Medicine, May 2024, Singapore, Singapore. ⟨hal-04627954⟩

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