Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8 - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Clinical Pharmacokinetics Année : 2019

Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8

Résumé

The in vivo mechanistic static model (IMSM) is an effective method to predict the magnitude of drug-drug interactions (DDIs) mediated by cytochromes.

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Pharmacologie
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Dates et versions

hal-04627130 , version 1 (27-06-2024)

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Michel Tod, Laurent Bourguignon, Nathalie Bleyzac, Sylvain Goutelle. Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8. Clinical Pharmacokinetics, 2019, 59 (6), pp.757-770. ⟨10.1007/s40262-019-00853-2⟩. ⟨hal-04627130⟩
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