Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8 - Archive ouverte HAL
Article Dans Une Revue Clinical Pharmacokinetics Année : 2019

Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8

Résumé

The in vivo mechanistic static model (IMSM) is an effective method to predict the magnitude of drug-drug interactions (DDIs) mediated by cytochromes.

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Pharmacologie

Sylvain Goutelle  : Connectez-vous pour contacter le contributeur

https://hal.science/hal-04627130

Soumis le : jeudi 27 juin 2024-12:02:29

Dernière modification le : vendredi 28 juin 2024-03:22:51

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Dates et versions

hal-04627130 , version 1 (27-06-2024)

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Citer

Michel Tod, Laurent Bourguignon, Nathalie Bleyzac, Sylvain Goutelle. Quantitative Prediction of Interactions Mediated by Transporters and Cytochromes: Application to Organic Anion Transporting Polypeptides, Breast Cancer Resistance Protein and Cytochrome 2C8. Clinical Pharmacokinetics, 2019, 59 (6), pp.757-770. ⟨10.1007/s40262-019-00853-2⟩. ⟨hal-04627130⟩

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