Self-cleaning products are commercially available to protect surfaces against soiling and avoid the high consumption of energy and chemical detergents necessary for cleaning. They are based on semiconductor oxides, mostly titanium dioxide (TiO2), which induce photocatalytic oxidation activity and superhydrophilicity. Therefore, we present an experimental procedure at a lab scale to assess the self-cleaning ability of various photocatalytic coatings (five TiO2-based commercial products and one lab-grade zinc oxide (ZnO) product) applied to mortar surfaces. The samples were artificially stained with three types of soiling: Congo red dye, diesel soot, and motor oil. They were exposed to the environmental cycle of UV illumination and water flow for two weeks and the changes in stain colors were first assessed with visual inspection. Then, spectrophotometry measurements were conducted before and after the self-cleaning experiment to calculate the color differences for each stain in the CIELab color space data. In addition, the coatings were characterized via X-ray diffraction analyses and water contact angle measurements. Results highlighted color changes for each stain and higher wettability (induced by OH radicals) of the coated surfaces, which favored surface washing and thus stain removal. Light also had a positive effect on the attenuation of the stains, particularly for the Congo red dye.