<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04606954</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-12T12:15:31+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">S-234 Strategies for monitoring of the internal exposome using self-sampling methods in the context of EU EPHOR project</title>
            <author role="aut">
              <persName>
                <forename type="first">Eline</forename>
                <surname>Verscheure</surname>
              </persName>
              <idno type="halauthorid">3170285-0</idno>
              <affiliation ref="#struct-92863"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Vivi</forename>
                <surname>Schlünssen</surname>
              </persName>
              <idno type="halauthorid">1333426-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Manolis</forename>
                <surname>Kogevinas</surname>
              </persName>
              <idno type="halauthorid">437615-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Barbara</forename>
                <surname>Harding</surname>
              </persName>
              <idno type="halauthorid">2558427-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Susan</forename>
                <surname>Peters</surname>
              </persName>
              <idno type="halauthorid">897713-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Roel</forename>
                <surname>Vermeulen</surname>
              </persName>
              <idno type="halauthorid">632759-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Rob</forename>
                <surname>Stierum</surname>
              </persName>
              <idno type="halauthorid">2512790-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Anjoeka</forename>
                <surname>Pronk</surname>
              </persName>
              <idno type="halauthorid">2346823-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Lode</forename>
                <surname>Godderis</surname>
              </persName>
              <idno type="halauthorid">1518319-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Manosij</forename>
                <surname>Ghosh</surname>
              </persName>
              <idno type="halauthorid">1818800-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">William</forename>
                <surname>Murch</surname>
              </persName>
              <idno type="halauthorid">3170286-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Anne Mette</forename>
                <surname>Lund Würtz</surname>
              </persName>
              <idno type="halauthorid">3169117-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Karin</forename>
                <surname>Broberg</surname>
              </persName>
              <idno type="halauthorid">1542961-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Shan</forename>
                <surname>Zienolddiny</surname>
              </persName>
              <idno type="halauthorid">3170287-0</idno>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Johanna</forename>
                <surname>Samulin-Erdem</surname>
              </persName>
              <idno type="halauthorid">3170288-0</idno>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Ines</forename>
                <surname>Saidi</surname>
              </persName>
              <email type="md5">6d4636ce6497ae551b089ca4423f231f</email>
              <email type="domain">inserm.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2024-06-10 12:50:24</date>
              <date type="whenModified">2026-05-12 11:54:07</date>
              <date type="whenReleased">2024-06-10 12:50:24</date>
              <date type="whenProduced">2021-01-25</date>
              <ref type="externalLink" target="https://oem.bmj.com/content/oemed/78/Suppl_1/A155.2.full.pdf"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="1409782">
                <persName>
                  <forename>Ines</forename>
                  <surname>Saidi</surname>
                </persName>
                <email type="md5">6d4636ce6497ae551b089ca4423f231f</email>
                <email type="domain">inserm.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04606954</idno>
            <idno type="halUri">https://hal.science/hal-04606954</idno>
            <idno type="halBibtex">verscheure:hal-04606954</idno>
            <idno type="halRefHtml">&lt;i&gt;28th International Symposium on Epidemiology in Occupational Health (EPICOH 2021)&lt;/i&gt;, Jan 2021, Virtual congress, France. pp.A155.2-A155, &lt;a target="_blank" href="https://dx.doi.org/10.1136/OEM-2021-EPI.424"&gt;&amp;#x27E8;10.1136/OEM-2021-EPI.424&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">28th International Symposium on Epidemiology in Occupational Health (EPICOH 2021), Jan 2021, Virtual congress, France. pp.A155.2-A155, &amp;#x27E8;10.1136/OEM-2021-EPI.424&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt/>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="invited" n="0">No</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
            <note type="proceedings" n="0">No</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">S-234 Strategies for monitoring of the internal exposome using self-sampling methods in the context of EU EPHOR project</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Eline</forename>
                    <surname>Verscheure</surname>
                  </persName>
                  <idno type="halauthorid">3170285-0</idno>
                  <affiliation ref="#struct-92863"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Vivi</forename>
                    <surname>Schlünssen</surname>
                  </persName>
                  <idno type="halauthorid">1333426-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Manolis</forename>
                    <surname>Kogevinas</surname>
                  </persName>
                  <idno type="halauthorid">437615-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Barbara</forename>
                    <surname>Harding</surname>
                  </persName>
                  <idno type="halauthorid">2558427-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Susan</forename>
                    <surname>Peters</surname>
                  </persName>
                  <idno type="halauthorid">897713-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Roel</forename>
                    <surname>Vermeulen</surname>
                  </persName>
                  <idno type="halauthorid">632759-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Rob</forename>
                    <surname>Stierum</surname>
                  </persName>
                  <idno type="halauthorid">2512790-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Anjoeka</forename>
                    <surname>Pronk</surname>
                  </persName>
                  <idno type="halauthorid">2346823-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Lode</forename>
                    <surname>Godderis</surname>
                  </persName>
                  <idno type="halauthorid">1518319-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Manosij</forename>
                    <surname>Ghosh</surname>
                  </persName>
                  <idno type="halauthorid">1818800-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">William</forename>
                    <surname>Murch</surname>
                  </persName>
                  <idno type="halauthorid">3170286-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Anne Mette</forename>
                    <surname>Lund Würtz</surname>
                  </persName>
                  <idno type="halauthorid">3169117-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Karin</forename>
                    <surname>Broberg</surname>
                  </persName>
                  <idno type="halauthorid">1542961-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Shan</forename>
                    <surname>Zienolddiny</surname>
                  </persName>
                  <idno type="halauthorid">3170287-0</idno>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Johanna</forename>
                    <surname>Samulin-Erdem</surname>
                  </persName>
                  <idno type="halauthorid">3170288-0</idno>
                </author>
              </analytic>
              <monogr>
                <meeting>
                  <title>28th International Symposium on Epidemiology in Occupational Health (EPICOH 2021)</title>
                  <date type="start">2021-01-25</date>
                  <date type="end">2021-01-28</date>
                  <settlement>Virtual congress</settlement>
                  <country key="FR">France</country>
                </meeting>
                <imprint>
                  <publisher>BMJ Publishing Group Ltd</publisher>
                  <biblScope unit="pp">A155.2-A155</biblScope>
                </imprint>
              </monogr>
              <idno type="doi">10.1136/OEM-2021-EPI.424</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <classCode scheme="halDomain" n="sdv">Life Sciences [q-bio]</classCode>
              <classCode scheme="halTypology" n="COMM">Conference papers</classCode>
              <classCode scheme="halOldTypology" n="COMM">Conference papers</classCode>
              <classCode scheme="halTreeTypology" n="COMM">Conference papers</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Introduction Working life exposures contribute significantly to non-communicable disease development. However, the challenge remains on how to map occupational exposures during the entire career and link exposures with health outcomes. In this context, the EU EPHOR project aims to characterize the internal exposome, by characterizing exposure biomarkers and biological pathways to link external exposure and health effects. While there is a range of strategies available to monitor the internal exposome, these conventional methods often require invasive collection of biological samples and/or high volumes. However, the ongoing COVID-19 pandemic forces us to look also at other approaches to obtain biological samples.Objective We aimed to explore the use of self-sampling techniques in an occupational exposome context.Methods We have conducted a semi-systematic literature review to identify self-sampling techniques used to generate high quality data on several biomarkers of exposure and effect. We are exploring the possibility of using these self-sampling techniques through a pilot study. A tiered analytical approach along with a biological sequence will be followed to efficiently analyze the samples (i.e. blood, urine, saliva, exhaled breath, exhaled breath aerosols and exhaled breath condensate) for a broad spectrum of biomarkers and omics. Additionally, non-invasive targeted and non-targeted exposome markers of acute lung function decline and inflammation will be developed through proteomic analysis of exhaled breath condensate (EBC), and exhaled breath VOCs using the ReCIVA Breath Sampler. These data will be integrated to generate signatures or ‘fingerprints’ of exposomes, at individual and group levels.Results and Conclusion The developed methodology will be applied in 2 cohorts within the EPHOR project: shift-workers and workers with asthma or allergic rhinitis to assess the internal exposure and elucidate biological pathways in disease development.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="institution" xml:id="struct-92863" status="VALID">
          <idno type="IdRef">026431297</idno>
          <idno type="ROR">https://ror.org/02495e989</idno>
          <orgName>Université Catholique de Louvain = Catholic University of Louvain</orgName>
          <orgName type="acronym">UCLouvain</orgName>
          <desc>
            <address>
              <addrLine>Place de l'Université 1, B-1348 Louvain-La-Neuve</addrLine>
              <country key="BE"/>
            </address>
            <ref type="url">https://www.uclouvain.be/fr</ref>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>