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Article Dans Une Revue American Journal of Tropical Medicine and Hygiene Année : 2023

Emerging Maripa Hantavirus as a Potential Cause of a Severe Health Threat in French Guiana

Anne Lavergne

Résumé

We describe the clinical parameters and management of nine confirmed cases of hantavirus pulmonary syndrome reported in French Guiana since 2008. All patients were admitted to Cayenne Hospital. Seven patients were men and the mean age was 48 years (range, 19–71 years). Two phases characterized the disease. The prodromal phase was characterized by fever (77.8%), myalgia (66.7%), and gastrointestinal symptoms (vomiting and diarrhea; 55.6%) starting, on average, 5 days before the illness phase, which was characterized by respiratory failure in all patients. Five patients died (55.6%) and the length of stay in the intensive care unit was 19 days (range, 11–28 days) for survivors. Detection of two back-to-back recent cases highlights the reason to screen for hantavirus infection during the nonspecific phase of the disease, in particular when concomitant pulmonary infection and digestive disorders are observed. Specific longitudinal serological surveys must also be used to identify other potential clinical forms of the disease in French Guiana.
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hal-04589042 , version 1 (27-05-2024)

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Séverine Matheus, Stéphanie Houcke, Guy Roger Lontsi Ngoula, Pablo Lecaros, Jean Marc Pujo, et al.. Emerging Maripa Hantavirus as a Potential Cause of a Severe Health Threat in French Guiana. American Journal of Tropical Medicine and Hygiene, 2023, 108 (5), pp.1014-1016. ⟨10.4269/ajtmh.22-0390⟩. ⟨hal-04589042⟩
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