Medical device development to quantify lung stiffness in smokers using magnetic resonance elastography
Résumé
Tobacco smoking is responsible for 80 % of lung cancer in Europe [1] and in 2040 the European commission aims to achieve a tobacco-free Europe. Smokers develop symptoms as a function of tobacco use estimated by the number of pack-years [2]. Current medical test is Computed Tomography (CT) to evaluate the morphological lung changes. However, CT uses X-rays, limiting regular follow up of patients. Based on our experience in fibrotic tissues [3], we have developed magnetic resonance elastography (MRE) to quantify themechanical properties of smoker lung. Of note, tobacco-related pathologies are the most preventable diseases and thus early detection and regular monitoring methods are essential. Our goal is to provide personalized cartography of lung stiffness which would 1) become a biomarker to prevent future lung disease and 2) trigger an awareness of the patient regarding the state of their lung function through a visual color scale.
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