Wearable electrocardiogram devices in patients with congenital long QT syndrome: The SMART-QT study - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Archives of cardiovascular diseases Année : 2024

Wearable electrocardiogram devices in patients with congenital long QT syndrome: The SMART-QT study

Résumé

Background: In patients with congenital long QT syndrome (LQTS), the risk of ventricular arrhythmia is correlated with the duration of the corrected QT interval and the changes in the ST-T wave pattern on the 12-lead surface electrocardiogram (12L-ECG). Remote monitoring of these variables could be useful. Aim: To evaluate the abilities of two wearable electrocardiogram devices (Apple Watch and KardiaMobile 6L) to provide reliable electrocardiograms in terms of corrected QT interval and ST-T wave patterns in patients with LQTS. Methods: In a prospective multicentre study (ClinicalTrials.gov identifier: NCT04728100), a 12L-ECG, a 6-lead KardiaMobile 6L electrocardiogram and two single-lead Apple Watch electrocardiograms were recorded in patients with LQTS. The corrected QT interval and ST-T wave patterns were evaluated manually. Results: Overall, 98 patients with LQTS were included; 12.2% were children and 92.8% had a pathogenic variant in an LQTS gene. The main genotypes were LQTS type 1 (40.8%), LQTS type 2 (36.7%) and LQTS type 3 (7.1%); rarer genotypes were also represented. When comparing the ST-T wave patterns obtained with the 12L-ECG, the level of agreement was moderate with the Apple Watch (k = 0.593) and substantial with the KardiaMobile 6L (k = 0.651). Regarding the corrected QT interval, the correlation with 12L-ECG was strong for the Apple Watch (r = 0.703 in lead II) and moderate for the KardiaMobile 6L (r = 0.593). There was a slight overestimation of corrected QT interval with the Apple Watch and a subtle underestimation with the KardiaMobile 6L. Conclusions: In patients with LQTS, the corrected QT interval and ST-T wave patterns obtained with the Apple Watch and the KardiaMobile 6L correlated with the 12L-ECG. Although wearable electrocardiogram devices cannot replace the 12L-ECG for the follow-up of these patients, they could be interesting additional monitoring tools.
Fichier principal
Vignette du fichier
2024 Deliniere et al., Wearable electrocardiogram.pdf (830.5 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04561476 , version 1 (06-05-2024)

Identifiants

Citer

Antoine Delinière, Francis Bessière, Leslie Placide, Jean-Luc Pasquié, Christelle Haddad, et al.. Wearable electrocardiogram devices in patients with congenital long QT syndrome: The SMART-QT study. Archives of cardiovascular diseases, In press, ⟨10.1016/j.acvd.2024.02.010⟩. ⟨hal-04561476⟩
0 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More