Global coastal areas are at risk due to geomorphological issues, climate change-induced sea-level rise, and increasing human population, settlements, and socioeconomic activities. Here, the study examines the vulnerability of the West African (WA) coast using six satellite-derived geophysical variables and two key socioeconomic parameters as indicators of coastal vulnerability index (CVI). These geophysical and socioeconomic variables are integrated to develop a CVI for the WA coast. Then, the regional hotspots of vulnerability with the main indicators that could influence how the WA coast behaves and can be managed are identified. The results indicate that 64, 17 and 19% of WA coastal areas had high to very high CVI, moderate CVI, and low to very low CVI, respectively. The study reveals that while geophysical variables contribute to coastal vulnerability in WA, socioeconomic factors, particularly high population growth and unsustainable human development at the coast, play a considerably larger role. Some sections of the WA coast are more vulnerable and exposed than others, particularly those in the region s northwestern and Gulf of Guinea regions. Climate change and human presence may amplify the vulnerability in these vulnerable areas in the future. Hence, future coastal economic development plans should be based on a deep understanding of local natural conditions, resource status, and geophysical parameters to prevent negative coastal ecosystem transformation. It is also essential to establish a coastal management plan that would facilitate the development of desired actions and stimulate sustainable management of West African coastal areas.