<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04549138</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-12T09:01:30+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Impact of a paediatric-adult care transition programme on the health status of patients with sickle cell disease: study protocol for a randomised controlled trial (the DREPADO trial)</title>
            <author role="aut">
              <persName>
                <forename type="first">Delphine</forename>
                <surname>Hoegy</surname>
              </persName>
              <email type="md5">eb4e83ecc824821248952488cb6dc022</email>
              <email type="domain">chu-lyon.fr</email>
              <idno type="idhal" notation="numeric">1169699</idno>
              <idno type="halauthorid" notation="string">1353498-1169699</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-8659-6073</idno>
              <affiliation ref="#struct-526139"/>
              <affiliation ref="#struct-300094"/>
              <affiliation ref="#struct-300192"/>
              <affiliation ref="#struct-222995"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Nathalie</forename>
                <surname>Bleyzac</surname>
              </persName>
              <idno type="halauthorid">1432810-0</idno>
              <affiliation ref="#struct-348446"/>
              <affiliation ref="#struct-35913"/>
              <affiliation ref="#struct-172478"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Alexandra</forename>
                <surname>Gauthier-Vasserot</surname>
              </persName>
              <idno type="halauthorid">1090008-0</idno>
              <affiliation ref="#struct-222995"/>
              <affiliation ref="#struct-93721"/>
              <affiliation ref="#struct-1005049"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Giovanna</forename>
                <surname>Cannas</surname>
              </persName>
              <idno type="halauthorid">842782-0</idno>
              <affiliation ref="#struct-222995"/>
              <affiliation ref="#struct-93721"/>
              <affiliation ref="#struct-1005049"/>
              <affiliation ref="#struct-300094"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Angélique</forename>
                <surname>Denis</surname>
              </persName>
              <email type="md5">6a292776814556f281c22d8305997bd2</email>
              <email type="domain">chu-lyon.fr</email>
              <idno type="idhal" notation="string">angelique-denis</idno>
              <idno type="idhal" notation="numeric">745264</idno>
              <idno type="halauthorid" notation="string">684232-745264</idno>
              <affiliation ref="#struct-300074"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Arnaud</forename>
                <surname>Hot</surname>
              </persName>
              <idno type="halauthorid">440510-0</idno>
              <affiliation ref="#struct-300094"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Yves</forename>
                <surname>Bertrand</surname>
              </persName>
              <idno type="halauthorid">2525267-0</idno>
              <affiliation ref="#struct-348446"/>
              <affiliation ref="#struct-222995"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pauline</forename>
                <surname>Occelli</surname>
              </persName>
              <email type="md5">76845a7fae67d305655c4f755438a7ad</email>
              <email type="domain">chu-lyon.fr</email>
              <idno type="idhal" notation="numeric">1366077</idno>
              <idno type="halauthorid" notation="string">472308-1366077</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-8384-8087</idno>
              <idno type="IDREF">https://www.idref.fr/147881781</idno>
              <idno type="VIAF">https://viaf.org/viaf/200168957</idno>
              <idno type="ISNI">http://isni.org/isni/0000000357584791</idno>
              <affiliation ref="#struct-421734"/>
              <affiliation ref="#struct-300074"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sandrine</forename>
                <surname>Touzet</surname>
              </persName>
              <email type="md5">803303de54e7e819d5cf6d74d34c15f5</email>
              <email type="domain">chu-lyon.fr</email>
              <idno type="idhal" notation="numeric">938506</idno>
              <idno type="halauthorid" notation="string">362341-938506</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-0354-7920</idno>
              <affiliation ref="#struct-421734"/>
              <affiliation ref="#struct-300074"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Claude</forename>
                <surname>Dussart</surname>
              </persName>
              <email type="md5">4d8d02528e9d8008836531bad36eef4c</email>
              <email type="domain">univ-lyon1.fr</email>
              <idno type="idhal" notation="string">dussartcl</idno>
              <idno type="idhal" notation="numeric">786325</idno>
              <idno type="halauthorid" notation="string">1322124-786325</idno>
              <idno type="ORCID">https://orcid.org/0000-0002-1091-9139</idno>
              <affiliation ref="#struct-526139"/>
              <affiliation ref="#struct-300074"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Audrey</forename>
                <surname>Janoly-Dumenil</surname>
              </persName>
              <idno type="idhal" notation="numeric">773049</idno>
              <idno type="halauthorid" notation="string">883207-773049</idno>
              <idno type="IDREF">https://www.idref.fr/080163637</idno>
              <affiliation ref="#struct-526139"/>
              <affiliation ref="#struct-300094"/>
              <affiliation ref="#struct-300192"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Roxanne</forename>
                <surname>HABLOT</surname>
              </persName>
              <email type="md5">15a85b6da9e1a60257ca84c13c75da37</email>
              <email type="domain">inist.fr</email>
            </editor>
            <funder ref="#projanr-54935"/>
            <funder>This work was supported by the French Ministry of Health, grant number 69HCL18_0039 as PREPS (Projet de Recherche sur la Performance du Système de Soins) 2017.</funder>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2024-07-16 17:47:46</date>
              <date type="whenModified">2026-04-23 14:50:05</date>
              <date type="whenReleased">2024-07-16 18:26:53</date>
              <date type="whenProduced">2020-02-10</date>
              <date type="whenEndEmbargoed">2024-07-16</date>
              <ref type="file" target="https://hal.science/hal-04549138v1/document">
                <date notBefore="2024-07-16"/>
              </ref>
              <ref type="file" subtype="greenPublisher" n="1" target="https://hal.science/hal-04549138v1/file/s13063-019-4009-9.pdf" id="file-4650507-4037049">
                <date notBefore="2024-07-16"/>
              </ref>
              <ref type="externalLink" target="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008523"/>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="1074726">
                <persName>
                  <forename>Roxanne</forename>
                  <surname>HABLOT</surname>
                </persName>
                <email type="md5">15a85b6da9e1a60257ca84c13c75da37</email>
                <email type="domain">inist.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04549138</idno>
            <idno type="halUri">https://hal.science/hal-04549138</idno>
            <idno type="halBibtex">hoegy:hal-04549138</idno>
            <idno type="halRefHtml">&lt;i&gt;Trials&lt;/i&gt;, 2020, 21 (1), pp.152. &lt;a target="_blank" href="https://dx.doi.org/10.1186/s13063-019-4009-9"&gt;&amp;#x27E8;10.1186/s13063-019-4009-9&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Trials, 2020, 21 (1), pp.152. &amp;#x27E8;10.1186/s13063-019-4009-9&amp;#x27E9;</idno>
            <availability status="restricted">
              <licence target="https://creativecommons.org/licenses/by/4.0/">CC BY 4.0 - Attribution<ref corresp="#file-4650507-4037049"/></licence>
            </availability>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="UNIV-ST-ETIENNE">Université Jean Monnet - Saint-Etienne</idno>
            <idno type="stamp" n="ENS-LYON">École Normale Supérieure de Lyon</idno>
            <idno type="stamp" n="UNIV-SAVOIE">Université Savoie Mont Blanc</idno>
            <idno type="stamp" n="HCL">Hospices Civils de Lyon</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="UNIV-LYON1">Université Claude Bernard - Lyon I</idno>
            <idno type="stamp" n="HEH" corresp="HCL">Hôpital Edouard Herriot</idno>
            <idno type="stamp" n="P2S" corresp="UNIV-LYON1">Parcours Santé Systémique - EA 4129</idno>
            <idno type="stamp" n="CIRI" corresp="UNIV-LYON1">Centre International de Recherche en Infectiologie</idno>
            <idno type="stamp" n="LIBM" corresp="UNIV-SAVOIE">Laboratoire Interuniversitaire de Biologie de la Motricité</idno>
            <idno type="stamp" n="UDL">UDL</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="UNIVERSITE-PARIS" corresp="UNIV-PARIS">Université Paris Cité</idno>
            <idno type="stamp" n="ANR">ANR</idno>
            <idno type="stamp" n="RESHAPE" corresp="UNIV-LYON1">Unité U1290 RESHAPE (RESearch on HealthcAre PErformance)</idno>
            <idno type="stamp" n="STAPS">STAPS</idno>
            <idno type="stamp" n="COLL-STAPS">COLL-STAPS</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Impact of a paediatric-adult care transition programme on the health status of patients with sickle cell disease: study protocol for a randomised controlled trial (the DREPADO trial)</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Delphine</forename>
                    <surname>Hoegy</surname>
                  </persName>
                  <email type="md5">eb4e83ecc824821248952488cb6dc022</email>
                  <email type="domain">chu-lyon.fr</email>
                  <idno type="idhal" notation="numeric">1169699</idno>
                  <idno type="halauthorid" notation="string">1353498-1169699</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-8659-6073</idno>
                  <affiliation ref="#struct-526139"/>
                  <affiliation ref="#struct-300094"/>
                  <affiliation ref="#struct-300192"/>
                  <affiliation ref="#struct-222995"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Nathalie</forename>
                    <surname>Bleyzac</surname>
                  </persName>
                  <idno type="halauthorid">1432810-0</idno>
                  <affiliation ref="#struct-348446"/>
                  <affiliation ref="#struct-35913"/>
                  <affiliation ref="#struct-172478"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Alexandra</forename>
                    <surname>Gauthier-Vasserot</surname>
                  </persName>
                  <idno type="halauthorid">1090008-0</idno>
                  <affiliation ref="#struct-222995"/>
                  <affiliation ref="#struct-93721"/>
                  <affiliation ref="#struct-1005049"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Giovanna</forename>
                    <surname>Cannas</surname>
                  </persName>
                  <idno type="halauthorid">842782-0</idno>
                  <affiliation ref="#struct-222995"/>
                  <affiliation ref="#struct-93721"/>
                  <affiliation ref="#struct-1005049"/>
                  <affiliation ref="#struct-300094"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Angélique</forename>
                    <surname>Denis</surname>
                  </persName>
                  <email type="md5">6a292776814556f281c22d8305997bd2</email>
                  <email type="domain">chu-lyon.fr</email>
                  <idno type="idhal" notation="string">angelique-denis</idno>
                  <idno type="idhal" notation="numeric">745264</idno>
                  <idno type="halauthorid" notation="string">684232-745264</idno>
                  <affiliation ref="#struct-300074"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Arnaud</forename>
                    <surname>Hot</surname>
                  </persName>
                  <idno type="halauthorid">440510-0</idno>
                  <affiliation ref="#struct-300094"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Yves</forename>
                    <surname>Bertrand</surname>
                  </persName>
                  <idno type="halauthorid">2525267-0</idno>
                  <affiliation ref="#struct-348446"/>
                  <affiliation ref="#struct-222995"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pauline</forename>
                    <surname>Occelli</surname>
                  </persName>
                  <email type="md5">76845a7fae67d305655c4f755438a7ad</email>
                  <email type="domain">chu-lyon.fr</email>
                  <idno type="idhal" notation="numeric">1366077</idno>
                  <idno type="halauthorid" notation="string">472308-1366077</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-8384-8087</idno>
                  <idno type="IDREF">https://www.idref.fr/147881781</idno>
                  <idno type="VIAF">https://viaf.org/viaf/200168957</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000357584791</idno>
                  <affiliation ref="#struct-421734"/>
                  <affiliation ref="#struct-300074"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sandrine</forename>
                    <surname>Touzet</surname>
                  </persName>
                  <email type="md5">803303de54e7e819d5cf6d74d34c15f5</email>
                  <email type="domain">chu-lyon.fr</email>
                  <idno type="idhal" notation="numeric">938506</idno>
                  <idno type="halauthorid" notation="string">362341-938506</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-0354-7920</idno>
                  <affiliation ref="#struct-421734"/>
                  <affiliation ref="#struct-300074"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Claude</forename>
                    <surname>Dussart</surname>
                  </persName>
                  <email type="md5">4d8d02528e9d8008836531bad36eef4c</email>
                  <email type="domain">univ-lyon1.fr</email>
                  <idno type="idhal" notation="string">dussartcl</idno>
                  <idno type="idhal" notation="numeric">786325</idno>
                  <idno type="halauthorid" notation="string">1322124-786325</idno>
                  <idno type="ORCID">https://orcid.org/0000-0002-1091-9139</idno>
                  <affiliation ref="#struct-526139"/>
                  <affiliation ref="#struct-300074"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Audrey</forename>
                    <surname>Janoly-Dumenil</surname>
                  </persName>
                  <idno type="idhal" notation="numeric">773049</idno>
                  <idno type="halauthorid" notation="string">883207-773049</idno>
                  <idno type="IDREF">https://www.idref.fr/080163637</idno>
                  <affiliation ref="#struct-526139"/>
                  <affiliation ref="#struct-300094"/>
                  <affiliation ref="#struct-300192"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">2453</idno>
                <idno type="issn">1745-6215</idno>
                <title level="j">Trials</title>
                <imprint>
                  <publisher>BioMed Central</publisher>
                  <biblScope unit="volume">21</biblScope>
                  <biblScope unit="issue">1</biblScope>
                  <biblScope unit="pp">152</biblScope>
                  <date type="datePub">2020-02-10</date>
                  <date type="dateEpub">2020-02-10</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1186/s13063-019-4009-9</idno>
              <idno type="pubmed">32039737</idno>
              <idno type="pubmedcentral">PMC7008523</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Paediatric-adult care transition</term>
                <term xml:lang="en">Sickle cell disease</term>
              </keywords>
              <classCode scheme="halDomain" n="stat">Statistics [stat]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Background Thanks to advancements in medical care, a majority of patients with sickle cell disease (SCD) worldwide live beyond 18 years of age, and therefore, patients initially followed in paediatric departments are then transferred to adult departments. This paediatric-adult care transition is a period with an increased risk of discontinuity of care and subsequent morbidity and mortality. During this period, the patient will have to manage new interlocutors and places of care, and personal issues related to the period of adolescence. To take into consideration all these aspects, an interesting approach is to use the whole system approach to the patient, as presented in the biopsychosocial approach. The aim of this trial is to evaluate the impact of the proposed biopsychosocial paediatric-adult transition programme. Methods The DREPADO study is a multicentre randomised control trial comparing a control group (Arm A) to an interventional group with a paediatric-adult transition programme based on a biopsychosocial approach (Arm B). To be included, patients should have the SS, SC, or Sβ form of sickle cell disease and be aged between 16 and 17 years. The randomisation in a 1:1 ratio assigns to Arm A or B. The primary outcome is the number of hospital admissions and emergencies for complications in the index hospital, in the 2 years after the first consultation in the adult department of care. Secondary outcomes consider the quality of life, but also include coping skills such as sense of self-efficacy and disease knowledge. To provide patient and parent knowledge and coping skills, the transition programme is composed of three axes: educational, psychological, and social, conducted individually and in groups. Discussion By providing self-care knowledge and coping skills related to SCD and therapeutics, helping empower patientsin relation to pain management and emotions, and facilitating the relationship to oneself, others, and care in Arm B of the DREPADO study, we believe that the morbidity and mortality of patients with SCD may be reduced after the proposed paediatric-adult transition programme. Trial registration ClinicalTrials.gov, ID: NCT03786549; registered on 17 December 2018; https://clinicaltrials.gov/ .</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-526139" status="VALID">
          <idno type="IdRef">198088469</idno>
          <idno type="RNSR">200715373J</idno>
          <orgName>Parcours santé systémique</orgName>
          <orgName type="acronym">P2S</orgName>
          <desc>
            <address>
              <addrLine>Faculté de Médecine Laënnec7-11 rue Guillaume Paradin69372 Lyon cedex 08</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="EA4129" active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300094" status="VALID">
          <idno type="ROR">https://ror.org/02qt1p572</idno>
          <orgName>Hôpital Edouard Herriot [CHU - HCL]</orgName>
          <desc>
            <address>
              <addrLine>5 Place d'Arsonval69003 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hopital-edouard-herriot</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-300192" status="VALID">
          <orgName>Université Claude Bernard Lyon 1 - Institut des Sciences Pharmaceutiques et Biologiques</orgName>
          <orgName type="acronym">UCBL ISPB</orgName>
          <desc>
            <address>
              <addrLine>8 avenue Rockfeller69373 LYON CEDEX 08</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://ispb.univ-lyon1.fr</ref>
          </desc>
          <listRelation>
            <relation active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
          </listRelation>
        </org>
        <org type="regrouplaboratory" xml:id="struct-222995" status="VALID">
          <idno type="IdRef">17825696X</idno>
          <idno type="ISNI">0000000404506033</idno>
          <idno type="RNSR">201320572J</idno>
          <idno type="ROR">https://ror.org/059sz6q14</idno>
          <idno type="Wikidata">Q30261449</idno>
          <orgName>Centre International de Recherche en Infectiologie</orgName>
          <orgName type="acronym">CIRI</orgName>
          <date type="start">2013-01-01</date>
          <desc>
            <address>
              <addrLine>21 avenue Tony Garnier 69365 Lyon Cedex 07</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://ciri.inserm.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-6818" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
            <relation active="#struct-194495" type="direct"/>
            <relation active="#struct-300284" type="direct"/>
            <relation active="#struct-1327915" type="indirect"/>
            <relation name="U1111" active="#struct-303623" type="direct"/>
            <relation name="UMR5308" active="#struct-441569" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-348446" status="VALID">
          <idno type="ROR">https://ror.org/0075rng13</idno>
          <orgName>Institut d'hématologie et d'oncologie pédiatrique [CHU - HCL]</orgName>
          <orgName type="acronym">IHOPe</orgName>
          <desc>
            <address>
              <addrLine>1 place Professeur Joseph Renault69008 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/institut-hematologie-et-oncologie-pediatrique-ihope</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-35913" status="OLD">
          <idno type="IdRef">166375942</idno>
          <idno type="RNSR">200315007D</idno>
          <orgName>Ciblage thérapeutique en Oncologie</orgName>
          <orgName type="acronym">EA3738</orgName>
          <date type="start">2003-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>UFR Faculté de Médecin Lyon-Sud-Charles Mérieux BP12165 Chemin du Grand Revoyet69921 OULLINS Cedex</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation name="EA3738" active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-172478" status="VALID">
          <orgName>Centre antipoison et de toxicovigilance (Lyon)</orgName>
          <orgName type="acronym">CAPTV Lyon</orgName>
          <desc>
            <address>
              <addrLine>Service Hospitalo-Universitaire de Pharmacologie et de Toxicologie de Lyon, Bâtiment A – 162 avenue Lacassagne, 69424 Lyon Cedex 03 – France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-300074" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-93721" status="VALID">
          <idno type="IdRef">185116175</idno>
          <idno type="RNSR">201622148J</idno>
          <idno type="ROR">https://ror.org/03sc1p174</idno>
          <orgName>Laboratoire Interuniversitaire de Biologie de la Motricité</orgName>
          <orgName type="acronym">LIBM</orgName>
          <date type="start">2016-01-01</date>
          <desc>
            <address>
              <addrLine>Faculté de Médecin Campus Santé Innovations - Bâtiment IRMIS - 10 rue de la Marandière 42270 Saint Priest en JarezUniversité Savoie Mont Blanc - Campus Scientifique - 73370 Le Bourget du LacUFR STAPS - Université Claude Bernard Lyon I - 27/29 Boulevard du 11 novembre 1918 - 69622 Villeurbanne Cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://libm.univ-st-etienne.fr/fr/index.html</ref>
          </desc>
          <listRelation>
            <relation name="EA7424" active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
            <relation name="EA7424" active="#struct-300284" type="direct"/>
            <relation active="#struct-1327915" type="indirect"/>
            <relation name="EA7424" active="#struct-432896" type="direct"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-1005049" status="VALID">
          <orgName>Laboratoire d'Excellence : Biogenèse et pathologies du globule rouge</orgName>
          <orgName type="acronym">Labex Gr-Ex</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Imagine Institute24, Boulevard du Montparnasse75015, Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.labex-grex.com/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-303171" type="direct"/>
            <relation active="#struct-303623" type="direct"/>
            <relation active="#struct-557826" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-300074" status="VALID">
          <idno type="IdRef">026534657</idno>
          <idno type="ROR">https://ror.org/01502ca60</idno>
          <orgName>Hospices Civils de Lyon</orgName>
          <orgName type="acronym">HCL</orgName>
          <desc>
            <address>
              <addrLine>3 Quai des Célestins69002 Lyon</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.chu-lyon.fr/fr/hospices-civils-de-lyon-hcl</ref>
          </desc>
        </org>
        <org type="laboratory" xml:id="struct-421734" status="OLD">
          <idno type="IdRef">203652991</idno>
          <idno type="RNSR">201622306F</idno>
          <orgName>Health Service and Performance Research</orgName>
          <orgName type="acronym">HESPER</orgName>
          <date type="start">2016-01-01</date>
          <date type="end">2020-12-31</date>
          <desc>
            <address>
              <addrLine>Site Lacassagne 162 Avenue Lacassagne69424 Lyon 3e</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.hesper.fr</ref>
          </desc>
          <listRelation>
            <relation name="EA7425" active="#struct-194495" type="direct"/>
            <relation active="#struct-301088" type="indirect"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-194495" status="VALID">
          <idno type="IdRef">026402823</idno>
          <idno type="ISNI">0000000121686185</idno>
          <idno type="ROR">https://ror.org/029brtt94</idno>
          <orgName>Université Claude Bernard Lyon 1</orgName>
          <orgName type="acronym">UCBL</orgName>
          <desc>
            <address>
              <addrLine>43, boulevard du 11 novembre 1918, 69622 Villeurbanne cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-lyon1.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301088" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-301088" status="VALID">
          <idno type="ROR">https://ror.org/01rk35k63</idno>
          <orgName>Université de Lyon</orgName>
          <desc>
            <address>
              <addrLine>92 rue Pasteur - CS 30122, 69361 Lyon Cedex 07</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.universite-lyon.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-6818" status="VALID">
          <idno type="IdRef">149154992</idno>
          <idno type="ISNI">0000000123319856</idno>
          <idno type="ROR">https://ror.org/04zmssz18</idno>
          <idno type="Wikidata">Q10159</idno>
          <orgName>École normale supérieure de Lyon</orgName>
          <orgName type="acronym">ENS de Lyon</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>15 parvis René Descartes - BP 7000 - 69342 Lyon Cedex 07</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.ens-lyon.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301088" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-300284" status="VALID">
          <idno type="IdRef">028209966</idno>
          <idno type="ISNI">0000 0001 2158 1682</idno>
          <idno type="ROR">https://ror.org/04yznqr36</idno>
          <idno type="Wikidata">Q623154</idno>
          <orgName>Université Jean Monnet - Saint-Étienne</orgName>
          <orgName type="acronym">UJM</orgName>
          <date type="start">1969-03-27</date>
          <date type="end">2025-01-01</date>
          <desc>
            <address>
              <addrLine>10, Rue Tréfilerie – CS 8230142023 Saint-Étienne Cedex 2</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-st-etienne.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1327915" type="direct"/>
          </listRelation>
        </org>
        <org type="regroupinstitution" xml:id="struct-1327915" status="VALID">
          <idno type="IdRef">285395831</idno>
          <orgName>Université Jean Monnet (EPSCPE)</orgName>
          <orgName type="acronym">UJM EPE</orgName>
          <date type="start">2025-01-01</date>
          <desc>
            <address>
              <addrLine>10 rue Tréfilerie42100 Saint-Etienne</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-st-etienne.fr/fr/index.html</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-303623" status="VALID">
          <idno type="IdRef">026388278</idno>
          <idno type="ROR">https://ror.org/02vjkv261</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>
            <address>
              <addrLine>101, rue de Tolbiac, 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-432896" status="VALID">
          <idno type="ROR">https://ror.org/04gqg1a07</idno>
          <orgName>Université Savoie Mont Blanc</orgName>
          <orgName type="acronym">USMB [Université de Savoie] [Université de Chambéry]</orgName>
          <date type="start">1979-10-01</date>
          <desc>
            <address>
              <addrLine>27, rue Marcoz - 73000 Chambéry</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.univ-smb.fr</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-303171" status="VALID">
          <idno type="IdRef">19077990X</idno>
          <idno type="ROR">https://ror.org/001z21q04</idno>
          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-557826" status="VALID">
          <idno type="IdRef">236453505</idno>
          <idno type="ISNI">0000 0004 7885 7602</idno>
          <idno type="ROR">https://ror.org/05f82e368</idno>
          <orgName>Université Paris Cité</orgName>
          <orgName type="acronym">UPCité</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>85 boulevard Saint-Germain75006 Paris</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://u-paris.fr/</ref>
          </desc>
        </org>
      </listOrg>
      <listOrg type="projects">
        <org type="anrProject" xml:id="projanr-54935" status="VALID">
          <idno type="anr">ANR-11-LABX-0051</idno>
          <orgName>GR-Ex</orgName>
          <desc>Biogenèse et pathologies du globule rouge</desc>
          <date type="start">2011</date>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>