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Article Dans Une Revue Synthesis: Journal of Synthetic Organic Chemistry Année : 2021

Contributing to the Study of Enzymatic and Chemical Glycosyl Transfer Through the Observation and Mimicry of Glycosyl Cations

Résumé

This account describes our efforts dedicated to: 1) the design of glycomimetics aimed at targeting therapeutically relevant carbohydrate processing enzymes, and 2) the observation, characterization, and exploitation of glycosyl cations as a tool for studying the glycosylation reaction. These findings have brought important data regarding this key ionic species as well as innovative strategies to access iminosugars of interest.

Domaines

Chimie organique
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Dates et versions

hal-04542796 , version 1 (11-04-2024)

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Yves Blériot. Contributing to the Study of Enzymatic and Chemical Glycosyl Transfer Through the Observation and Mimicry of Glycosyl Cations. Synthesis: Journal of Synthetic Organic Chemistry, 2021, 53 (05), pp.904-924. ⟨10.1055/s-0040-1706073⟩. ⟨hal-04542796⟩
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