This entry is adapted from 10.3390/ijms25063132. Dendrimers, arborescent macromolecules exhibiting a large number of functional groups at their surface, appeared as naturally attractive targets to consider as TPA chromophores. Indeed, dendrimers are a special kind of perfectly defined hyperbranched polymers constructed stepwise from a multifunctional core at the periphery of which can be grafted a large density and variety of chromophores.