This research aims to address the increasing regulatory and environmental challenges associated with refrigeration systems by fostering innovations. Refrigeration systems, as socio-technical entities, present a challenge due to their complexity, diverse stakeholders, and evolving regulatory constraints. Identifying opportunities for innovation in such intricate systems is further complicated by various performance-contributing factors. The Radical Innovation Design (RID) methodology, designed for aligning design solutions with activities, proves effective in pinpointing and prioritizing innovation targets across the lifecycle of a complex system. In this study, data from interviews and practices in the retail refrigeration sector inform the RID methodology. Two sets of results are presented. Firstly, a knowledge book of the socio-technical system is categorized into four RID dimensions: usage situations, user profiles, current problems, and existing solutions. The second set includes outcomes from two RID decision-support tools: the RID Comparator evaluates the effectiveness of existing solutions, while the RID Compass identifies three improvement areas - poor adaptation of new technical clusters, disrupted stakeholder interaction processes, and a lack of common tools. These results underwent validation through expert iterations, leading to a recommended hybrid solution involving the development of an integrated model-based platform.