ptlmapper: Useful genetic tool allowing to discriminate individuals by comparing the distribution of their phenotype and to map the genetic loci responsible for specific distributions - Archive ouverte HAL
Logiciel Année : 2024

ptlmapper: Useful genetic tool allowing to discriminate individuals by comparing the distribution of their phenotype and to map the genetic loci responsible for specific distributions

Résumé

This package contains functions that are used to map single-cell Probabilistic Trait Loci (scPTL). The principle of scPTL mapping is to consider a distribution of single-cell traits as the phenotype of a (multicellular) individual, to acquire this phenotype in many individuals, and to scan the genome for DNA variants that change this phenotype.

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Florent Chuffart, Magali Richard, Daniel Jost, Gael Yvert. ptlmapper: Useful genetic tool allowing to discriminate individuals by comparing the distribution of their phenotype and to map the genetic loci responsible for specific distributions. 2024, ⟨swh:1:dir:fdb7c18c6cc1da4e23be844d76960975de7d58b4;origin=https://github.com/fchuffar/ptlmapper;visit=swh:1:snp:b5ad098a35fef37940d0859e1c93d62daef2b508;anchor=swh:1:rev:c5068be2f281eab0e315cdfca29f1d5278d97617⟩. ⟨hal-04523653⟩
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