Latest Trends in Lipase-Catalyzed Synthesis of Ester Carbohydrate Surfactants: From Key Parameters to Opportunities and Future Development
Résumé
Carbohydrate-based surfactants are amphiphilic compounds containing hydrophilic moieties
linked to hydrophobic aglycones. More specifically, carbohydrate esters are biosourced and
biocompatible surfactants derived from inexpensive renewable raw materials (sugars and fatty acids).
Their unique properties allow them to be used in various areas, such as the cosmetic, food, and
medicine industries. These multi-applications have created a worldwide market for biobased surfactants
and consequently expectations for their production. Biobased surfactants can be obtained from
various processes, such as chemical synthesis or microorganism culture and surfactant purification. In
accordance with the need for more sustainable and greener processes, the synthesis of these molecules
by enzymatic pathways is an opportunity. This work presents a state-of-the-art lipase action mode,
with a focus on the active sites of these proteins, and then on four essential parameters for optimizing
the reaction: type of lipase, reaction medium, temperature, and ratio of substrates. Finally, this review
discusses the latest trends and recent developments, showing the unlimited potential for optimization
of such enzymatic syntheses.
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