<?xml version="1.0" encoding="utf-8"?>
<TEI xmlns="http://www.tei-c.org/ns/1.0" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:hal="http://hal.archives-ouvertes.fr/" xmlns:gml="http://www.opengis.net/gml/3.3/" xmlns:gmlce="http://www.opengis.net/gml/3.3/ce" version="1.1" xsi:schemaLocation="http://www.tei-c.org/ns/1.0 http://api.archives-ouvertes.fr/documents/aofr-sword.xsd">
  <teiHeader>
    <fileDesc>
      <titleStmt>
        <title>HAL TEI export of hal-04445635</title>
      </titleStmt>
      <publicationStmt>
        <distributor>CCSD</distributor>
        <availability status="restricted">
          <licence target="https://creativecommons.org/publicdomain/zero/1.0/">CC0 1.0 - Universal</licence>
        </availability>
        <date when="2026-05-15T21:33:02+02:00"/>
      </publicationStmt>
      <sourceDesc>
        <p part="N">HAL API Platform</p>
      </sourceDesc>
    </fileDesc>
  </teiHeader>
  <text>
    <body>
      <listBibl>
        <biblFull>
          <titleStmt>
            <title xml:lang="en">Hydrogen inhalation: in vivo rat genotoxicity tests</title>
            <author role="aut">
              <persName>
                <forename type="first">Cordélia</forename>
                <surname>Salomez-Ihl</surname>
              </persName>
              <email type="md5">33c1af4a2d715405120a2fd5f097a74f</email>
              <email type="domain">chu-grenoble.fr</email>
              <idno type="idhal" notation="numeric">1406318</idno>
              <idno type="halauthorid" notation="string">3046705-1406318</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-0756-7221</idno>
              <idno type="IDREF">https://www.idref.fr/272681040</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/IZY-8622-2023</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/CWJ-1950-2022</idno>
              <idno type="VIAF">https://viaf.org/viaf/52170000865871902796</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/IZY-8622-2023</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/CWJ-1950-2022</idno>
              <affiliation ref="#struct-1043049"/>
              <affiliation ref="#struct-257328"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Stéphane</forename>
                <surname>Tanguy</surname>
              </persName>
              <idno type="halauthorid">5920-0</idno>
              <affiliation ref="#struct-1043057"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Jean-Pierre</forename>
                <surname>Alcaraz</surname>
              </persName>
              <idno type="halauthorid">128563-0</idno>
              <affiliation ref="#struct-1043049"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Chloé</forename>
                <surname>Davin</surname>
              </persName>
              <idno type="halauthorid">3046706-0</idno>
              <affiliation ref="#struct-1043049"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Victor</forename>
                <surname>Pascal-Moussellard</surname>
              </persName>
              <idno type="halauthorid">3046707-0</idno>
              <affiliation ref="#struct-1043057"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Mariem</forename>
                <surname>Jabeur</surname>
              </persName>
              <idno type="halauthorid">3046708-0</idno>
              <affiliation ref="#struct-1043049"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Pierrick</forename>
                <surname>Bedouch</surname>
              </persName>
              <email type="md5">df87b984e786efcad038fbcca99ee653</email>
              <email type="domain">chu-grenoble.fr</email>
              <idno type="idhal" notation="string">pierrickbedouch</idno>
              <idno type="idhal" notation="numeric">774510</idno>
              <idno type="halauthorid" notation="string">384548-774510</idno>
              <idno type="IDREF">https://www.idref.fr/067288758</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-2245-0160</idno>
              <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=MbXsEckAAAAJ</idno>
              <idno type="ISNI">http://isni.org/isni/0000000123687368</idno>
              <idno type="VIAF">https://viaf.org/viaf/173641003</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/M-6169-2014</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/MGW-7580-2025</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/M-6169-2014</idno>
              <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/MGW-7580-2025</idno>
              <affiliation ref="#struct-1043049"/>
              <affiliation ref="#struct-257328"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Ludovic</forename>
                <surname>Le Hégarat</surname>
              </persName>
              <email type="md5">821cca656a021d6aabd338f00e5be495</email>
              <email type="domain">afssa.fr</email>
              <idno type="idhal" notation="string">lehegaratl</idno>
              <idno type="idhal" notation="numeric">881776</idno>
              <idno type="halauthorid" notation="string">467787-881776</idno>
              <idno type="ORCID">https://orcid.org/0000-0003-3494-4109</idno>
              <idno type="IDREF">https://www.idref.fr/083908560</idno>
              <idno type="VIAF">https://viaf.org/viaf/208157546</idno>
              <idno type="ISNI">http://isni.org/isni/0000000358597842</idno>
              <affiliation ref="#struct-564150"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Valérie</forename>
                <surname>Fessard</surname>
              </persName>
              <email type="md5">b8375f1ad153ef62d6c395afbf5e56b8</email>
              <email type="domain">afssa.fr</email>
              <idno type="idhal" notation="numeric">881770</idno>
              <idno type="halauthorid" notation="string">406675-881770</idno>
              <idno type="ORCID">https://orcid.org/0000-0001-9046-9117</idno>
              <idno type="IDREF">https://www.idref.fr/117918792</idno>
              <idno type="VIAF">https://viaf.org/viaf/219515633</idno>
              <idno type="ISNI">http://isni.org/isni/0000000140370020</idno>
              <affiliation ref="#struct-564150"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Anne-Louise</forename>
                <surname>Blier</surname>
              </persName>
              <email type="md5">c1ffb6544b2b40b88bb594ff5b52b5eb</email>
              <email type="domain">anses.fr</email>
              <idno type="idhal" notation="numeric">1373552</idno>
              <idno type="halauthorid" notation="string">2689648-1373552</idno>
              <affiliation ref="#struct-564150"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Sylvie</forename>
                <surname>Huet</surname>
              </persName>
              <email type="md5">6dcb4f246dac842c0a2037874b92cae2</email>
              <email type="domain">anses.fr</email>
              <idno type="idhal" notation="numeric">1025395</idno>
              <idno type="halauthorid" notation="string">50716-1025395</idno>
              <affiliation ref="#struct-564150"/>
            </author>
            <author role="aut">
              <persName>
                <forename type="first">Philippe</forename>
                <surname>Cinquin</surname>
              </persName>
              <idno type="halauthorid">134652-0</idno>
              <affiliation ref="#struct-1043049"/>
              <affiliation ref="#struct-257328"/>
            </author>
            <author role="crp">
              <persName>
                <forename type="first">François</forename>
                <surname>Boucher</surname>
              </persName>
              <idno type="halauthorid">246032-0</idno>
              <affiliation ref="#struct-1043049"/>
            </author>
            <editor role="depositor">
              <persName>
                <forename>Stéphane</forename>
                <surname>Tanguy</surname>
              </persName>
              <email type="md5">41484c13f4ce797604ec0b29e1ff2520</email>
              <email type="domain">univ-grenoble-alpes.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>
            <edition n="v1" type="current">
              <date type="whenSubmitted">2024-02-08 08:33:43</date>
              <date type="whenModified">2026-03-26 16:30:05</date>
              <date type="whenReleased">2024-02-08 08:33:43</date>
              <date type="whenProduced">2024-02</date>
            </edition>
            <respStmt>
              <resp>contributor</resp>
              <name key="171555">
                <persName>
                  <forename>Stéphane</forename>
                  <surname>Tanguy</surname>
                </persName>
                <email type="md5">41484c13f4ce797604ec0b29e1ff2520</email>
                <email type="domain">univ-grenoble-alpes.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>
            <distributor>CCSD</distributor>
            <idno type="halId">hal-04445635</idno>
            <idno type="halUri">https://hal.science/hal-04445635</idno>
            <idno type="halBibtex">salomezihl:hal-04445635</idno>
            <idno type="halRefHtml">&lt;i&gt;Mutation Research - Genetic Toxicology and Environmental Mutagenesis&lt;/i&gt;, 2024, 894, pp.503736. &lt;a target="_blank" href="https://dx.doi.org/10.1016/j.mrgentox.2024.503736"&gt;&amp;#x27E8;10.1016/j.mrgentox.2024.503736&amp;#x27E9;&lt;/a&gt;</idno>
            <idno type="halRef">Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2024, 894, pp.503736. &amp;#x27E8;10.1016/j.mrgentox.2024.503736&amp;#x27E9;</idno>
            <availability status="restricted"/>
          </publicationStmt>
          <seriesStmt>
            <idno type="stamp" n="ANSES">Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail</idno>
            <idno type="stamp" n="UGA">HAL Grenoble Alpes</idno>
            <idno type="stamp" n="IMAG">IMAG</idno>
            <idno type="stamp" n="CNRS">CNRS - Centre national de la recherche scientifique</idno>
            <idno type="stamp" n="INPG">Institut polytechnique de Grenoble</idno>
            <idno type="stamp" n="TIMC-IMAG">TIMC</idno>
            <idno type="stamp" n="TIMC-IMAG-PRETA" corresp="TIMC-IMAG">PRETA : Physiologie cardio-Respiratoire Expérimentale Théorique et Appliquée</idno>
            <idno type="stamp" n="AGREENIUM">Archive ouverte en agrobiosciences</idno>
            <idno type="stamp" n="UNIV-LYON">Université de Lyon</idno>
            <idno type="stamp" n="UGA-EPE">Université Grenoble Alpes [2020-*]</idno>
            <idno type="stamp" n="TEST-UGA">TEST-UGA</idno>
          </seriesStmt>
          <notesStmt>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>
            <biblStruct>
              <analytic>
                <title xml:lang="en">Hydrogen inhalation: in vivo rat genotoxicity tests</title>
                <author role="aut">
                  <persName>
                    <forename type="first">Cordélia</forename>
                    <surname>Salomez-Ihl</surname>
                  </persName>
                  <email type="md5">33c1af4a2d715405120a2fd5f097a74f</email>
                  <email type="domain">chu-grenoble.fr</email>
                  <idno type="idhal" notation="numeric">1406318</idno>
                  <idno type="halauthorid" notation="string">3046705-1406318</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-0756-7221</idno>
                  <idno type="IDREF">https://www.idref.fr/272681040</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/IZY-8622-2023</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/CWJ-1950-2022</idno>
                  <idno type="VIAF">https://viaf.org/viaf/52170000865871902796</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/IZY-8622-2023</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/CWJ-1950-2022</idno>
                  <affiliation ref="#struct-1043049"/>
                  <affiliation ref="#struct-257328"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Stéphane</forename>
                    <surname>Tanguy</surname>
                  </persName>
                  <idno type="halauthorid">5920-0</idno>
                  <affiliation ref="#struct-1043057"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Jean-Pierre</forename>
                    <surname>Alcaraz</surname>
                  </persName>
                  <idno type="halauthorid">128563-0</idno>
                  <affiliation ref="#struct-1043049"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Chloé</forename>
                    <surname>Davin</surname>
                  </persName>
                  <idno type="halauthorid">3046706-0</idno>
                  <affiliation ref="#struct-1043049"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Victor</forename>
                    <surname>Pascal-Moussellard</surname>
                  </persName>
                  <idno type="halauthorid">3046707-0</idno>
                  <affiliation ref="#struct-1043057"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Mariem</forename>
                    <surname>Jabeur</surname>
                  </persName>
                  <idno type="halauthorid">3046708-0</idno>
                  <affiliation ref="#struct-1043049"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Pierrick</forename>
                    <surname>Bedouch</surname>
                  </persName>
                  <email type="md5">df87b984e786efcad038fbcca99ee653</email>
                  <email type="domain">chu-grenoble.fr</email>
                  <idno type="idhal" notation="string">pierrickbedouch</idno>
                  <idno type="idhal" notation="numeric">774510</idno>
                  <idno type="halauthorid" notation="string">384548-774510</idno>
                  <idno type="IDREF">https://www.idref.fr/067288758</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-2245-0160</idno>
                  <idno type="GOOGLE SCHOLAR">https://scholar.google.fr/citations?user=MbXsEckAAAAJ</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000123687368</idno>
                  <idno type="VIAF">https://viaf.org/viaf/173641003</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/M-6169-2014</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/MGW-7580-2025</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/M-6169-2014</idno>
                  <idno type="RESEARCHERID">http://www.researcherid.com/rid/http://www.researcherid.com/rid/MGW-7580-2025</idno>
                  <affiliation ref="#struct-1043049"/>
                  <affiliation ref="#struct-257328"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Ludovic</forename>
                    <surname>Le Hégarat</surname>
                  </persName>
                  <email type="md5">821cca656a021d6aabd338f00e5be495</email>
                  <email type="domain">afssa.fr</email>
                  <idno type="idhal" notation="string">lehegaratl</idno>
                  <idno type="idhal" notation="numeric">881776</idno>
                  <idno type="halauthorid" notation="string">467787-881776</idno>
                  <idno type="ORCID">https://orcid.org/0000-0003-3494-4109</idno>
                  <idno type="IDREF">https://www.idref.fr/083908560</idno>
                  <idno type="VIAF">https://viaf.org/viaf/208157546</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000358597842</idno>
                  <affiliation ref="#struct-564150"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Valérie</forename>
                    <surname>Fessard</surname>
                  </persName>
                  <email type="md5">b8375f1ad153ef62d6c395afbf5e56b8</email>
                  <email type="domain">afssa.fr</email>
                  <idno type="idhal" notation="numeric">881770</idno>
                  <idno type="halauthorid" notation="string">406675-881770</idno>
                  <idno type="ORCID">https://orcid.org/0000-0001-9046-9117</idno>
                  <idno type="IDREF">https://www.idref.fr/117918792</idno>
                  <idno type="VIAF">https://viaf.org/viaf/219515633</idno>
                  <idno type="ISNI">http://isni.org/isni/0000000140370020</idno>
                  <affiliation ref="#struct-564150"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Anne-Louise</forename>
                    <surname>Blier</surname>
                  </persName>
                  <email type="md5">c1ffb6544b2b40b88bb594ff5b52b5eb</email>
                  <email type="domain">anses.fr</email>
                  <idno type="idhal" notation="numeric">1373552</idno>
                  <idno type="halauthorid" notation="string">2689648-1373552</idno>
                  <affiliation ref="#struct-564150"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Sylvie</forename>
                    <surname>Huet</surname>
                  </persName>
                  <email type="md5">6dcb4f246dac842c0a2037874b92cae2</email>
                  <email type="domain">anses.fr</email>
                  <idno type="idhal" notation="numeric">1025395</idno>
                  <idno type="halauthorid" notation="string">50716-1025395</idno>
                  <affiliation ref="#struct-564150"/>
                </author>
                <author role="aut">
                  <persName>
                    <forename type="first">Philippe</forename>
                    <surname>Cinquin</surname>
                  </persName>
                  <idno type="halauthorid">134652-0</idno>
                  <affiliation ref="#struct-1043049"/>
                  <affiliation ref="#struct-257328"/>
                </author>
                <author role="crp">
                  <persName>
                    <forename type="first">François</forename>
                    <surname>Boucher</surname>
                  </persName>
                  <idno type="halauthorid">246032-0</idno>
                  <affiliation ref="#struct-1043049"/>
                </author>
              </analytic>
              <monogr>
                <idno type="halJournalId" status="VALID">17241</idno>
                <idno type="issn">1383-5718</idno>
                <title level="j">Mutation Research - Genetic Toxicology and Environmental Mutagenesis</title>
                <imprint>
                  <publisher>Elsevier</publisher>
                  <biblScope unit="volume">894</biblScope>
                  <biblScope unit="pp">503736</biblScope>
                  <date type="datePub">2024-02</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.mrgentox.2024.503736</idno>
              <idno type="pubmed">38432775</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>
            <langUsage>
              <language ident="en">English</language>
            </langUsage>
            <textClass>
              <keywords scheme="author">
                <term xml:lang="en">Bone marrow micronucleus test</term>
                <term xml:lang="en">Comet assay</term>
                <term xml:lang="en">ICH guidelines</term>
                <term xml:lang="en">Molecular hydrogen</term>
                <term xml:lang="en">in vivo genotoxicity</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.tox">Life Sciences [q-bio]/Toxicology</classCode>
              <classCode scheme="halDomain" n="sdv.bbm.gtp">Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN]</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halOldTypology" n="ART">Journal articles</classCode>
              <classCode scheme="halTreeTypology" n="ART">Journal articles</classCode>
              <classCode scheme="https://namespace.ccsd.cnrs.fr/hal/metadata/afssa_thematique" n="154">Conception et validation de méthodes en toxicologie</classCode>
            </textClass>
            <abstract xml:lang="en">
              <p>Preclinical and clinical studies have shown that molecular hydrogen (H2) has anti-oxidant, anti-inflammatory, and anti-apoptotic properties. Safety data are available in the literature and acute toxicity has been tested in isolated cells and laboratory animals. We have evaluates the genotoxicity of H2 in vivo in rats after 72 h exposure, following the International Council for Harmonization guidelines ICH S2 (R1). The study was conducted on three groups of male Wistar rats: a negative control group, a positive control group receiving methyl methanesulfonate, and a H2-treated group receiving a 3.1% H2 gas mixture for 72 h. Alkaline comet, formamidopyrimidine DNA glycosylase (Fpg)-modified comet and bone marrow micronucleus assays were performed. H2 exposure increased neither comet-tail DNA intensity (DNA damage) nor frequency of "hedgehogs" in blood, liver, lungs, or bronchoalveolar lavage fluid. No increase in Fpg-sensitive sites in lungs, no induction of micronucleus formation, and no imbalance of immature erythrocyte to total erythrocyte ratio (IME%) was observed in rats exposed to H2. The ICH S2 (R1) test-battery revealed no in vivo genotoxicity in Wistar rats after 72 h inhalation of a mixture containing 3.1% H2.</p>
            </abstract>
          </profileDesc>
        </biblFull>
      </listBibl>
    </body>
    <back>
      <listOrg type="structures">
        <org type="laboratory" xml:id="struct-1043049" status="VALID">
          <idno type="IdRef">14728936X</idno>
          <idno type="ISNI">0000 0004 4687 1979</idno>
          <idno type="RNSR">199511969L</idno>
          <idno type="ROR">https://ror.org/03985kf35</idno>
          <orgName>Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525</orgName>
          <orgName type="acronym">TIMC</orgName>
          <date type="start">2021-01-01</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.timc.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-301767" type="direct"/>
            <relation name="UMR5525" active="#struct-441569" type="direct"/>
            <relation active="#struct-1042703" type="direct"/>
            <relation active="#struct-1043329" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-257328" status="VALID">
          <idno type="IdRef">034137076</idno>
          <idno type="ROR">https://ror.org/041rhpw39</idno>
          <orgName>CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble</orgName>
          <orgName type="acronym">CHUGA</orgName>
          <desc>
            <address>
              <addrLine>CS 1021738043 Grenoble cedex 9</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.chu-grenoble.fr/</ref>
          </desc>
        </org>
        <org type="researchteam" xml:id="struct-1043057" status="VALID">
          <orgName>Physiologie cardio-Respiratoire Expérimentale Théorique et Appliquée</orgName>
          <orgName type="acronym">TIMC-PRETA</orgName>
          <date type="start">2021-01-01</date>
          <desc>
            <address>
              <addrLine>Domaine de la Merci, 38706 La Tronche, France</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.timc.fr/preta</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1043049" type="direct"/>
            <relation active="#struct-301767" type="indirect"/>
            <relation name="UMR5525" active="#struct-441569" type="indirect"/>
            <relation active="#struct-1042703" type="indirect"/>
            <relation active="#struct-1043329" type="indirect"/>
          </listRelation>
        </org>
        <org type="laboratory" xml:id="struct-564150" status="VALID">
          <idno type="IdRef">196700000</idno>
          <idno type="RNSR">201023295G</idno>
          <orgName>Laboratoire de Fougères - ANSES</orgName>
          <desc>
            <address>
              <addrLine>10B rue Claude Bourgelat, Javené CS 40608 35306 Fougères Cedex</addrLine>
              <country key="FR"/>
            </address>
          </desc>
          <listRelation>
            <relation active="#struct-301715" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301767" status="VALID">
          <idno type="ROR">https://ror.org/01c7wz417</idno>
          <orgName>VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement</orgName>
          <orgName type="acronym">VAS</orgName>
          <date type="start">2010-01-01</date>
          <desc>
            <address>
              <addrLine>Université de Lyon, VetAgro Sup, 69280 Marcy l'Etoile (campus vétérinaire); Université de Clermont, VetAgro Sup, 63370 Lempdes (campus agronomique)</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.vetagro-sup.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-441569" status="VALID">
          <idno type="IdRef">02636817X</idno>
          <idno type="ISNI">0000000122597504</idno>
          <idno type="ROR">https://ror.org/02feahw73</idno>
          <orgName>Centre National de la Recherche Scientifique</orgName>
          <orgName type="acronym">CNRS</orgName>
          <date type="start">1939-10-19</date>
          <desc>
            <address>
              <country key="FR"/>
            </address>
            <ref type="url">https://www.cnrs.fr/</ref>
          </desc>
        </org>
        <org type="regroupinstitution" xml:id="struct-1042703" status="VALID">
          <idno type="IdRef">240648315</idno>
          <idno type="ROR">https://ror.org/02rx3b187</idno>
          <orgName>Université Grenoble Alpes</orgName>
          <orgName type="acronym">UGA</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>Adresse CS 40700 - 38058 Grenoble cedex</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.univ-grenoble-alpes.fr</ref>
          </desc>
        </org>
        <org type="institution" xml:id="struct-1043329" status="VALID">
          <idno type="IdRef">026388804</idno>
          <idno type="ROR">https://ror.org/05sbt2524</idno>
          <orgName>Institut polytechnique de Grenoble - Grenoble Institute of Technology</orgName>
          <orgName type="acronym">Grenoble INP</orgName>
          <date type="start">2020-01-01</date>
          <desc>
            <address>
              <addrLine>46 avenue Félix Viallet 38031 Grenoble Cedex 1</addrLine>
              <country key="FR"/>
            </address>
            <ref type="url">http://www.grenoble-inp.fr/</ref>
          </desc>
          <listRelation>
            <relation active="#struct-1042703" type="direct"/>
          </listRelation>
        </org>
        <org type="institution" xml:id="struct-301715" status="VALID">
          <idno type="IdRef">148269761</idno>
          <idno type="ISNI">0000 0001 0584 7022</idno>
          <idno type="ROR">https://ror.org/0471kz689</idno>
          <idno type="Wikidata">Q392520</idno>
          <orgName>Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail</orgName>
          <orgName type="acronym">ANSES</orgName>
          <date type="start">2010-07-01</date>
          <desc>
            <address>
              <addrLine>14 rue Pierre et Marie Curie94701 MAISONS-ALFORT Cedex</addrLine>
              <country key="FR"/>
            </address>
          </desc>
        </org>
      </listOrg>
    </back>
  </text>
</TEI>